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Article
Electrocatalytic hydrogenation of lignin-derived compounds in heteropolyacid fluidized system
Lignin is an important source of biomass energy and chemical raw material. The combination of lignin depolymerization and electrocatalytic hydrogenation (ECH) is a very important pathway to convert lignin to h...
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Article
Gradient-based algorithms for multi-objective bi-level optimization
Multi-objective bi-level optimization (MOBLO) addresses nested multi-objective optimization problems common in a range of applications. However, its multi-objective and hierarchical bi-level nature makes it no...
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Article
Branching laws of Klein four-symmetric pairs for \(\textrm{Sp}(n,\mathbb {R})\)
For the real symplectic groups \(G=\textrm{Sp}(n,\mathbb {R})\) G
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Article
Open AccessCerebellar Transcranial Direct Current Stimulation Modulates Anticipatory Postural Adjustments in Healthy Adults
During forward swinging of the arm, the central nervous system must anticipate the effect of upraising upon the body. Little is known about the cerebellar network that coordinates these anticipatory postural a...
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Article
Open AccessUnveiling heterogeneity of hysteresis in perovskite thin films
The phenomenon of current–voltage hysteresis observed in perovskite-based optoelectronic devices is a critical issue that complicates the accurate assessment of device parameters, thereby impacting performance...
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Article
High-Efficient Hydrogenolysis of Xylose to Polyols Over Ni-W/CeO2 Catalysts
Catalytic hydrogenolysis of xylose to ethylene glycol (EG) and 1,2-propanediol (1,2-PG) is an important way for the high-value valorization of biomass. Herein, Ni-W/CeO2 catalysts prepared by incipient-wetness im...
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Article
Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models
It is imperative to develop novel therapeutics to overcome chemoresistance, a significant obstacle in the clinical management of prostate cancer (PCa) and other cancers.
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Article
Corrosion protection of NiTi alloy via micro-arc oxidation doped with ZnO nanoparticles and polyacrylamide sol–gel sealing
NiTi alloy is considered to have great application potential in the fabrication of metal implant materials. However, the NiTi alloy still suffers from some disadvantages, such as poor corrosion resistance and ...
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Article
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML
Although high-dose, multiagent chemotherapy has improved leukemia survival rates, treatment outcomes remain poor in high-risk subsets, including acute myeloid leukemia (AML) and acute lymphoblastic leukemia (A...
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Article
Research on the Influence of Water-Laser Coupling Cavity and Nozzle Structure on the Flow Characteristics of Water Beam Fiber
In the water jet-guided laser processing technology, the stability and impact characteristics of water jet have an important impact on the processing quality. In order to study the influence of the structure o...
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Article
Open AccessLigand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice
Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding protein that transports phosphatidylcholine (PC) between cellular membranes. To better understand the protective metaboli...
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Article
Experimental study of the thermal effects and processing in CW laser-assisted turning of SiC ceramics
In order to realize plastic processing in the continuous-wave laser-assisted machining (LAM) of SiC ceramics, the thermal effect of the laser and the influence of preheating the surface morphology and the lase...
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Chapter and Conference Paper
Multi-modal Scene Recognition Based on Global Self-attention Mechanism
With the rapid development of deep neural network and the emergence of multi-modal acquisition devices, multi-modal scene recognition based on deep neural network has been known as a research hotspot. In view ...
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Chapter and Conference Paper
Cultivating Researcher-Sensibility in Novice Designers: Exploring Genre-Specific Heuristics for Game Evaluation in a Design Studio
This paper presents an eight-day design studio that teaches heuristic evaluation of games to third-year bachelor students at the School of Design, Southern University of Science and Technology. Through this co...
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Article
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells
Ovarian cancer is one of the most common gynecologic malignancies in women and has a poor prognosis. Taxanes are a class of standard first-line chemotherapeutic agents for the treatment of ovarian cancer. Howe...
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Article
Discrete decomposability of restrictions of \(({\mathfrak {g}},K)\) -modules for \((G,G^\sigma )\) with an automorphism \(\sigma \) of even order
Let G be a noncompact connected simple Lie group, and \(G^\sigma \) G ...
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Article
Open AccessCandidate gene screening for lipid deposition using combined transcriptomic and proteomic data from Nanyang black pigs
Lower selection intensities in indigenous breeds of Chinese pig have resulted in obvious genetic and phenotypic divergence. One such breed, the Nanyang black pig, is renowned for its high lipid deposition and ...
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Article
Open AccessMelphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells
Treatment-induced cardiotoxicity is a leading noncancer-related cause of acute and late onset morbidity and mortality in cancer patients on antineoplastic drugs such as melphalan—increasing clinical case repor...
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Article
Open AccessDiscovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma
Glioblastoma (GBM) is a universally lethal tumor with frequently overexpressed or mutated epidermal growth factor receptor (EGFR). NADPH quinone oxidoreductase 1 (NQO1) and glutathione-S-transferase Pi 1 (GSTP...
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Article
Open AccessHigh expression of MKK3 is associated with worse clinical outcomes in African American breast cancer patients
African American women experience a twofold higher incidence of triple-negative breast cancer (TNBC) and are 40% more likely to die from breast cancer than women of other ethnicities. However, the molecular ba...
