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Article
Determination of Soil Organic Matter and Total Nitrogen from Visible Near-Infrared Spectroscopy by Multivariate Models and Variable Selection Techniques
The status of soil nutrient content is a fundamental factor affecting changes in soil quality, influencing the growth conditions and yield levels of crops. The practicality of combining visible and near-infrar...
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Article
Open AccessMindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial
To evaluate mindfulness-based intervention for hypertension with depression and/or anxiety.
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Article
Open AccessSingle-cell RNA-seq analysis decodes the kidney microenvironment induced by polystyrene microplastics in mice receiving a high-fat diet
In recent years, the environmental health issue of microplastics has aroused an increasingly significant concern. Some studies suggested that exposure to polystyrene microplastics (PS-MPs) may lead to renal in...
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Article
Construction of cuproptosis signature based on bioinformatics and experimental validation in clear cell renal cell carcinoma
Cuproptosis was defined as a novel nonapoptotic cell death pathway and its potential function in clear cell renal cell carcinoma (ccRCC) remains unclear.
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Article
Influence of diamine moieties on the gas permeation performances of polyimide: perspectives from experiment and simulation
This work reported the gas permeation performances of three 6FDA-based polyimides, including 6FDA-DABA, 6FDA-ODA and 6FDA-TFDB, which contain polar amide, flexible ether, and bulky –CF3 groups in diamine units, r...
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Article
Open AccessProteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitor
The tyrosine kinase inhibitor (TKI) Sunitinib is one the therapies approved for advanced renal cell carcinoma. Here, we undertake proteogenomic profiling of 115 tumors from patients with clear cell renal cell ...
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Article
Open AccessUltra-fast and accurate electron ionization mass spectrum matching for compound identification with million-scale in-silico library
Spectrum matching is the most common method for compound identification in mass spectrometry (MS). However, some challenges limit its efficiency, including the coverage of spectral libraries, the accuracy, and...
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Article
Association of computed tomography-based body composition with survival in metastatic renal cancer patient received immunotherapy: a multicenter, retrospective study
To investigate the association of computed tomography
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Article
Dynamical analysis for an age-structured model of eating disorders
This paper investigates the diffusion of eating disorders by constructing an age-structured model with an age-dependent diffusion coefficient. Compared with earlier articles, we introduce the process of re-sus...
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Article
Open AccessBIS-guided sedation prevents the cough reaction of patients under general anaesthesia caused by extubation: a randomized controlled trial
The multiple modes of SARS-CoV-2 transmission including airborne, droplet, contact and faecal–oral transmissions that cause coronavirus disease 2019 (COVID-19) contribute to a public threat to the lives of peo...
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Article
Open AccessCompound lidocaine/prilocaine cream combined with tetracaine prevents cough caused by extubation after general anaesthesia: a randomised controlled trial
Coughing caused by tracheal extubation is common following general anaesthesia. Heavy aerosol production by coughing during recovery from general anaesthesia in patients with respiratory infections (especially...
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Article
Open AccessProbability distribution characteristics of summer extreme precipitation in **njiang, China during 1970–2021
Based on the daily precipitation data of 96 stations in **njiang, China, from 1970 to 2021, the trend of summer extreme precipitation indices and their regional characteristics are analyzed. The generalized ex...
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Article
Open AccessProteogenomic characterization of MiT family translocation renal cell carcinoma
Microphthalmia transcription factor (MiT) family translocation renal cell carcinoma (tRCC) is a rare type of kidney cancer, which is not well characterized. Here we show the comprehensive proteogenomic analysi...
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Article
Review of novel materials as photosensitizers towards the bottleneck of photodynamic therapy
Photodynamic therapy (PDT) is a safe and effective therapeutic option for the management of cancer and other diseases. However, the issues of light (dose and wavelength), tumour selectivity of photosensitizers...
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Article
Prognostic value, DNA variation and immunologic features of a tertiary lymphoid structure-related chemokine signature in clear cell renal cell carcinoma
The tumor microenvironment (TME) and tertiary lymphoid structures (TLS) affect the occurrence and development of cancers. How the immune contexture interacts with the phenotype of clear cell renal cell carcino...
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Article
Influence of structural isomerism on the aggregate structure and barrier performance of polyimide: evaluation by experiment and simulation
A novel carbazole-bearing diamine (3,6-CPDA) has been synthesized by Suzuki coupling reaction, which is an isomer of our previously reported diamine 2,7-CPDA. In comparison with 2,7-CPDA, the substituted posit...
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Article
Open AccessDeciphering the role of miR-187-3p/LRFN1 axis in modulating progression, aerobic glycolysis and immune microenvironment of clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant genitourinary cancers with high recurrence risk worldwide. Recently, multi-omics data facilitate obtaining a molecular landscape of t...
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Article
Open AccessThe efficacy and safety of acupuncture and nicotine replacement therapy for smoking cessation: study protocol for a randomized controlled trial
Tobacco hazard is one of the most serious public health problems, accounting for up to 6 million deaths worldwide p.a. We aim to determine the efficacy and safety of acupuncture and/or nicotine replacement the...
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Article
Open AccessIntegrated proteogenomic characterization of urothelial carcinoma of the bladder
Urothelial carcinoma (UC) is the most common pathological type of bladder cancer, a malignant tumor. However, an integrated multi-omics analysis of the Chinese UC patient cohort is lacking.
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Article
Open AccessHeterologous expression of pediocin/papA in Bacillus subtilis
Listeria monocytogenes is a food-borne pathogen. Pediocin is a group IIα bacteriocin with anti-listeria activity that is naturally produced by Pediococcus acidilactic and Lactobacillus plantarum. The pedA/papA ge...
