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  1. Article

    Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation

    To investigate the action of isothiafludine (NZ-4), a derivative of bis-heterocycle tandem pairs from the natural product leucamide A, on the replication cycle of hepatitis B virus (HBV) in vitro and in vivo.

    Li Yang, Li-** Shi, Hai-jun Chen, **an-Kun Tong in Acta Pharmacologica Sinica (2014)