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    Role of recombinant plasmid pEGFP-N1-IGF-1 transfection in alleviating osteoporosis in ovariectomized rats

    Decreased levels of serum insulin-like growth factor-1 (IGF-1) have been proven to cause osteoporosis. Gene transfer of IGF-1 offers an attractive technology to treat skeletal metabolic disorders including ost...

    Hai Chun Liu, Hua Zhao, Jian Chen, Wen Liang Wu… in Journal of Molecular Histology (2013)