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  1. No Access

    Article

    Improvement of Slee** Beauty Transposon System Enabling Efficient and Stable Protein Production

    The most essential goal in the field of biopharmaceuticals is to develop cell lines with higher protein yields. To this goal, the Slee** Beauty (SB) transposon-based expression system has been developed as a...

    Yun Haeng Lee, Ji Yun Park, Eun Seon Song in Biotechnology and Bioprocess Engineering (2022)

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    Article

    Bacterial Artificial Chromosome-based Protein Expression Platform Using the Tol2 Transposon System

    Conventional vector systems, including plasmid-based vectors, are mainly used in mammalian cells for the production of biopharmaceuticals. Plasmid-based vectors express transgene by the random integration of r...

    Myeong Uk Kuk, Ji Yun Park, Eun Seon Song in Biotechnology and Bioprocess Engineering (2022)

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    Article

    Rapid and Efficient BAC Recombineering: Gain & Loss Screening System

    Recombineering has been developed to modify bacterial artificial chromosome (BAC) via homologous recombination. Nevertheless, as a screening strategy to identify the correct clone was not properly developed, i...

    Myeong Uk Kuk, Yun Haeng Lee, Jae Won Kim in Biotechnology and Bioprocess Engineering (2021)

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    Article

    Cre/Lox-based RMCE for Site-specific Integration in CHO Cells

    Traditional cell line development is based on random genomic integration of transgenes. Random integration leads to unpredictable expression and results in clonal heterogeneity requiring a tedious screening pr...

    Jaewon Kim, Yun Haeng Lee, Myeong Uk Kuk in Biotechnology and Bioprocess Engineering (2021)

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    Article

    Oxygen permeation and oxidative coupling of methane with NiFe2O4-Gd0.1Ce0.9O2-δ composite membrane

    Oxygen permeability and oxidative coupling of methane (OCM) characteristics of a 30 vol.% NiFe2O4-70 vol.% Gd0.1Ce0.9O2-δ (NFO-GDC) composite membrane were systematically investigated by varying operational condi...

    Yeong A. Lee, Ji Haeng Yu, Hana Yoon, Dong-Woo Cho, Kyubock Lee, Chung-Yul Yoo in Ionics (2021)

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    Article

    Validation of analytical methods for organochlorine pesticide detection in shellfish and cephalopods by GC–MS/MS

    This study validated the analysis of organochlorine pesticides (OCPs) in shellfish and cephalopods using a gas chromatograph equipped with a mass spectrometry (GC–MS/MS), and monitored residual pesticide level...

    Sung-Min Hwang, Haeng-Un Lee, Jung-Bok Kim in Food Science and Biotechnology (2020)

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    Article

    Comparison of acrylamide and furan concentrations, antioxidant activities, and volatile profiles in cold or hot brew coffees

    The aim of this study was to investigate the formation of furan and acrylamide and to compare antioxidant capacities and volatile compounds in cold or hot brewed coffees. Cold brews were prepared at 5 °C and 2...

    Da-eun Kang, Haeng-Un Lee, Munkhtugs Davaatseren in Food Science and Biotechnology (2020)

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    Article

    Migration study of caprolactam from polyamide 6 sheets into food simulants

    Caprolactam, used in manufacturing polyamide (PA) 6, may threaten human health. Here, PA 6 sheets were produced by using a twin-screw extruder to evaluate its safety. Caprolactam migration concentrations from ...

    Hyun Ju Song, Yoonjee Chang, Ji Sou Lyu, Mi Yong Yon in Food Science and Biotechnology (2018)

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    Article

    Green lipped mussel oil complex suppresses lipopolysaccharide stimulated inflammation via regulating nuclear factor-κB and mitogen activated protein kinases signaling in RAW264.7 murine macrophages

    Here we investigated the effect of green lipped mussel oil complex (GLMOC) on inflammation and underlying mechanism in lipopolysaccharide stimulated RAW264.7 murine macrophage cells. GLMOC containing green li...

    **g Chen, Cheng Bao, Se Haeng Cho, Hong ** Lee in Food Science and Biotechnology (2017)

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    Article

    Physicochemical properties of enzyme-treated waxy rice flour and expansion properties of Gangjung (a traditional Korean oil-puffed rice snack)

    Long stee** process of waxy rice involved in Gangjung production is essential for obtaining good quality Gangjung, but it causes many related problems. The objective was to examine physiochemical properties of ...

    Haeng Ran Kim, Kyung Mi Kim, Ju-Hye Lee, Sang-Ho Yoo in Food Science and Biotechnology (2016)

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    Article

    Chiisanenside, a new triterpene glycoside from the fruits of Acanthopanax chiisanensis

    A new triterpene glycoside was isolated from the fruits of Acanthopanax chiisanensis and identified as 3-O-β-d-[(6-carboxymethyl)-glucopyranosyl-(1 → 3)-β-d-glucuronopyranosyl]-olean-12-en-28-oic acid by spectral...

    Jeong Min Lee, Jaemin Lee, Seon Haeng Cho, Sang-Won Lee in Applied Biological Chemistry (2016)

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    Article

    Application of Thermo-luminescence (TL) Method for the Identification of Food Mixtures Containing Irradiated Ingredients

    Thermo-luminescence (TL) method was employed to identify irradiated garlic or ginger powder mixed at different proportions into the food base. The identification of irradiation was carried out by analyzing the...

    Byeong-Keun Kim, Cheong-Tae Kim, Soo Hyun Park, Jeong-Eun Lee in Food Analytical Methods (2015)

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    Article

    Characterization and in Vitro Inhibition Studies of Bacillus anthracis FtsZ: A Potential Antibacterial Target

    FtsZ is an essential bacterial cell division protein that is an attractive target for the development of antibacterial agents. FtsZ is a homologue of eukaryotic tubulin, has GTPase activity, and forms a ring-t...

    Hae-Chul Park, Vinayakumar Gedi, June-Haeng Cho in Applied Biochemistry and Biotechnology (2014)

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    Article

    Estrogen-like activity of Adenophora triphylla var. japonica water extract in MCF-7 cells

    This study investigated the estrogen-like activity of Adenophora triphylla var. japonica, which has been shown to have pharmacological activities. Water extracts from A. triphylla (ATWE) could bind to estrogen re...

    Young Min Lee, Ji Hyun Bae, Song Yee Nam, Hwan Hee Jang in Food Science and Biotechnology (2013)

  15. No Access

    Article

    Sensory characteristics and cross-cultural comparisons of consumer acceptability for Gochujang dressing

    This study was conducted to identify the sensory profiles of gochujang dressing prepared with different formulations, and to compare hedonic responses crossculturally. Gochujang dressing samples were prepared by ...

    Jae-Hee Hong, Kyu-Won Lee, Seo** Chung, Lana Chung in Food Science and Biotechnology (2012)

  16. No Access

    Article

    Tolerance of Saccharomyces cerevisiae K35 to lignocellulose-derived inhibitory compounds

    The hydrolysis which converts polysaccharides to the fermentable sugars for yeast’s lingocellulosic ethanol production also generates byproducts which inhibit the ethanol production. To investigate the extent ...

    Hawon Lee, Dae Haeng Cho, Yong Hwan Kim in Biotechnology and Bioprocess Engineering (2011)

  17. No Access

    Article

    Preparation of multifunctional polymeric micelles for antiviral treatment

    In this study, a poly(L-lactic acid)-b-poly(ethylene glycol) (PLLA-b-PEG) diblock copolymer modified with a sialic acid derivative (methyl-b-neuraminic acid: mNA) was prepared for the development and application ...

    Yong Sik Ahn, Hye Jung Baik, Bo Reum Lee, Eun Seong Lee in Macromolecular Research (2010)

  18. No Access

    Article

    Paclitaxel-polyurethane film for anti-cancer drug delivery: Film characterization and preliminary in vivo study

    Polyurethane (PU) films incorporated with an anti-cancer drug paclitaxel (PTX) were prepared using a solvent casting method for potential applications to stent-based drug delivery and the local treatment of ma...

    Sung-Gwon Kang, Se Chul Lee, Seong Hoon Choi, Sangsoo Park in Macromolecular Research (2010)

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    Article

    Development of glucose sensor using two-photon adsorbed photopolymerization

    A novel glucose sensor was constructed, and its analytical potential examined. A chip-type three-electrode system for use in a flow-type electrochemical glucose sensor was fabricated using a UV lithography tec...

    Jong Min Kim, Jung-** Park, Haeng-Ja Lee in Bioprocess and Biosystems Engineering (2010)

  20. No Access

    Article

    Anti-Helicobacter pylori diarylheptanoid identified in the rhizome of Alpinia officinarum

    The antibacterial activity of materials derived from the rhizome of Alpinia officinarum (Zingiberaceae) against Helicobacter pylori ATCC 43504, ATCC 700392, and ATCC 700824 was examined using paper-disc diffusion...

    Haeng-Byung Lee, Hyun-Kyung Lee, Jun-Ran Kim in Journal of the Korean Society for Applied … (2009)

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