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  1. Article

    Open Access

    Blood vessel organoids generated by base editing and harboring single nucleotide variation in Notch3 effectively recapitulate CADASIL-related pathogenesis

    Human blood vessel organoids (hBVOs) offer a promising platform for investigating vascular diseases and identifying therapeutic targets. In this study, we focused on in vitro modeling and therapeutic target findi...

    Yu** Ahn, Ju-Hyun An, Hae-Jun Yang, Wi-Jae Lee, Sang-Hee Lee… in Molecular Neurobiology (2024)

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  2. Article

    Open Access

    Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis

    Despite numerous studies on the molecular switches governing the conversion of stemness to differentiation in embryonic stem cells (ESCs), little is known about the involvement of the retromer complex. Under n...

    Seon-A Choi, Young-Hyun Kim, Young-Ho Park, Hae-Jun Yang… in Cell Death & Differentiation (2019)

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