7 Result(s)

Article

Rationale and design of the PHOspholamban RElated CArdiomyopathy intervention STudy (i-PHORECAST)

The p.Arg14del (c.40_42delAGA) phospholamban (PLN) pathogenic variant is a founder mutation that causes dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM). Carriers are at increased risk of m...

W. P. te Rijdt, E. T. Hoorntje, R. de Brouwer, A. Oomen… in Netherlands Heart Journal (2022)

Article

Patient perspectives on priorities for research on conventional and sex- and gender-related cardiovascular risk factors

Recently, cardiovascular disease (CVD) research has focused on sex- and gender-related cardiovascular risk factors, in addition to conventional risk factors. This raises the question which factors are perceive...

R. Bolijn, I. Schalkers, H. L. Tan, A. E. Kunst… in Netherlands Heart Journal (2020)

Article

Atrial fibrillation mimicking ventricular fibrillation confuses an automated external defibrillator

M. Hulleman, M. T. Blom, A. Bardai, H. L. Tan, R. W. Koster in Netherlands Heart Journal (2018)

Article

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC–MAPKs–AP-1 pathway

It is intriguing that some pan-caspase inhibitors such as zVAD-fmk (zVAD) are capable of inducing necrotic cell death in a selected group of cells. As earlier reports from our laboratory have ruled out the ori...

Y-T Wu, H-L Tan, Q Huang, X-J Sun, X Zhu, H-M Shen in Cell Death & Differentiation (2011)

Article

Retraction Note: A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress

The authors would like to retract the above article. Recently, the authors were alerted by the journal's editors to some discrepancies in their data. After a careful review, sufficient errors and mistakes were...

Q Huang, Y-T Wu, H-L Tan, C-N Ong, H-M Shen in Cell Death & Differentiation (2010)

Article

A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress

Under oxidative stress, poly(ADP-ribose) polymerase-1 (PARP-1) is activated and contributes to necrotic cell death through ATP depletion. On the other hand, oxidative stress is known to stimulate autophagy, an...

Q Huang, Y-T Wu, H-L Tan, C-N Ong, H-M Shen in Cell Death & Differentiation (2009)

Article

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

At present, the signaling pathways controlling reactive nitrogen species (RNS)-induced non-apoptotic cell death are relatively less understood. In this work, various RNS donors are found to induce caspase-inde...

Y-T Wu, S Zhang, Y-S Kim, H-L Tan, M Whiteman, C-N Ong… in Cell Death & Differentiation (2008)