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Open AccessPolyrotaxane-based supramolecular theranostics
The development of smart theranostic systems with favourable biocompatibility, high loading efficiency, excellent circulation stability, potent anti-tumour activity, and multimodal diagnostic functionalities i...
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Article
Open AccessA discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy
Photodynamic therapy is an effective alternative to traditional treatments due to its minimally invasive nature, negligible systemic toxicity, fewer side effects, and avoidance of drug resistance. However, it ...
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Article
Open AccessSupramolecular peptide constructed by molecular Lego allowing programmable self-assembly for photodynamic therapy
Peptide self-assemblies with multiple nanostructures have great potentials in functional biomaterials, and yet the tedious and costly covalent peptide modification and the lack of facile controllability on sel...
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Article
Open AccessIs lobe specific lymph node dissection adequate for cN0–1 non-small cell lung cancer?
This study aims to explore whether lobe specific lymph node dissection (LND) is adequate for cN0–1 non-small cell lung cancer (NSCLC) or not.
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Article
Open AccessPredictors of postoperative complication and prolonged intensive care unit stay after complete pericardiectomy in tuberculous constrictive pericarditis
The risk factors of postoperative outcomes after pericardiectomy in tuberculous constrictive pericarditis have still been unclear. This study aimed to investigate the predictors of postoperative complication a...
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Open AccessHybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
Effectively activating macrophages against cancer is promising but challenging. In particular, cancer cells express CD47, a ‘don’t eat me’ signal that interacts with signal regulatory protein alpha (SIRPα) on ...
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Comparison of the diagnostic efficacy of the CapitalBio Mycobacterium real-time polymerase chain reaction detection test and Xpert MTB/RIF in smear-negative pulmonary tuberculosis
To compare the diagnostic efficacy of CapitalBio Mycobacterium real-time polymerase chain reaction (RT-PCR) detection test and the first-generation Xpert MTB/RIF in smear-negative pulmonary tuberculosis (PTB). In...
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Article
Pillararene-based supramolecular systems for theranostics and bioapplications
As an emerging type of important macrocycles for supramolecular chemistry, pillararenes and their derivatives have been widely studied and applied in numerous fields, which intensively promotes the development...
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Open AccessEvaluation of the stability of cucurbit[8]uril-based ternary host−guest complexation in physiological environment and the fabrication of a supramolecular theranostic nanomedicine
Supramolecular theranostics have exhibited promising potentials in disease diagnosis and therapy by taking advantages of the dynamic and reversible nature of non-covalent interactions. It is extremely importan...
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Open AccessThe optimal duration of anti-tuberculous therapy before pericardiectomy in constrictive tuberculous pericarditis
It is unclear about the duration of anti-tuberculous therapy before pericardiectomy (DATT) in the patients with constrictive tuberculous pericarditis. This study aims to explore the optimal DATT and its impact...
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Open AccessThe bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery
Lymphatic system is identified the second vascular system after the blood circulation in mammalian species, however the research on lymphatic system has long been hampered by the lack of comprehensive imaging ...
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Open AccessPredictive value of matrix metalloprotease 9 on surgical outcomes after pericardiectomy
The effects of matrix metalloproteases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expressions on the patients with constrictive pericarditis undergoing pericardiectomy remain unclear. This stud...
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Open AccessTEDC2 correlated with prognosis and immune microenvironment in lung adenocarcinoma
Tubulin epsilon and delta complex 2 (TEDC2) is a protein coding gene whose functions are poorly identified yet. This study aimed to identify the role of TEDC2 in prognosis and immune microenvironment of lung a...
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Open AccessA possible combined appraisal pattern: predicting the prognosis of patients after esophagectomy
To investigate the predictive merit of combined preoperative nutritional condition and systemic inflammation on the prognosis of patients receiving esophagectomy, with the assessment of model construction to e...
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Article
Open AccessA lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection
The respiratory system, especially the lung, is the key site of pathological injury induced by SARS-CoV-2 infection. Given the low feasibility of targeted delivery of antibodies into the lungs by intravenous a...
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Open AccessSeparation of benzene and toluene associated with vapochromic behaviors by hybrid[4]arene-based co-crystals
The combination of macrocyclic chemistry with co-crystal engineering has promoted the development of materials with vapochromic behaviors in supramolecular science. Herein, we develop a macrocycle co-crystal b...
