21 Result(s)
within
Guo** Tan
Life Sciences
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Article
Effects of Surface Mulching on Soil Water Temperature, Physiological Characteristics and Yield of Maize
In order to explore the cultivation techniques for increasing maize yield and water efficient utilization in the semi-arid area of Jilin Province, China, a field experiment was carried out in Taonan City, the ...
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Article
Exosomes loaded with circPARD3 promotes EBV-miR-BART4-induced stemness and cisplatin resistance in nasopharyngeal carcinoma side population cells through the miR-579-3p/SIRT1/SSRP1 axis
To explore the effects of exosomes loaded with circular RNA PARD3 on EBV-miR-BART4-induced stemness and resistance of cisplatin in nasopharyngeal carcinoma side population (NPC-SP) cells through the miR-579-3p...
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Article
Open AccessThe CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor with a poor median survival of less than 15 months. However, clinical strategies and effective therapies are limited. Here, we found that th...
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Article
Effects of straw returning on soil moisture and maize yield in semi-humid area
The purpose of this study was to control the effects of different tillage and straw returning methods on the temporal and spatial changes of soil moisture, photosynthetic characteristics of maize leaves, maize...
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Article
Open AccessAnalysis and review of trichomes in plants
Trichomes play a key role in the development of plants and exist in a wide variety of species.
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Protocol
Antibody Aggregate Removal Using a Mixed-Mode Chromatography Resin
In monoclonal antibody (mAb) production, aggregates represent a major class of product-related impurities that needs to be removed by the downstream process. Protein A chromatography is generally less effectiv...
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Article
The role of Caspase-1/GSDMD-mediated pyroptosis in Taxol-induced cell death and a Taxol-resistant phenotype in nasopharyngeal carcinoma regulated by autophagy
Taxol has been widely used as a first-line chemotherapeutic agent for the treatment of advanced nasopharyngeal carcinoma (NPC). However, acquired drug resistance has caused great difficulties in clinical treat...
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Article
Transcriptional regulation of a leucine-responsive regulatory protein for directly controlling lincomycin biosynthesis in Streptomyces lincolnensis
Leucine-responsive regulatory proteins (Lrps) are a family of transcription factors involved in diverse biological processes in bacteria. So far, molecular mechanism of Lrps for regulating antibiotics biosynth...
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Article
Biodetection and bioremediation of copper ions in environmental water samples using a temperature-controlled, dual-functional Escherichia coli cell
Although a variety of whole-cell biosensors and biosorbents have been developed for detection and removal of heavy metal contaminants, few whole cells can be applied to both monitoring and remediation of coppe...
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Article
Corrections to: Enhanced lincomycin production by co‑overexpression of metK1 and metK2 in Streptomyces lincolnensis
In the online published article, row value “pIB139-metK1-metK2” in table 1 has been processed incorrectly. The correct table is given below
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Article
Enhanced lincomycin production by co-overexpression of metK1 and metK2 in Streptomyces lincolnensis
Streptomyces lincolnensis is generally utilized for the production of lincomycin A (Lin-A), a clinically useful antibiotic to treat Gram-positive bacterial infections. Three methylation steps, catalyzed by three ...
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Article
Open AccessThe FOXM1–ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells
Paclitaxel is clinically used as a first-line chemotherapeutic regimen for several cancer types, including head and neck cancers. However, acquired drug resistance results in the failure of therapy, metastasis...
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Article
A new approach for improving epothilone B yield in Sorangium cellulosum by the introduction of vgb epoF genes
Epothilone B has drawn great attention due to its much stronger anticancer activity and weaker side effects compared with taxol. The relative low yield of epothilone B limited its application. In this study, w...
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Article
ZmWAK, a quantitative resistance gene to head smut in maize, improves yield performance by reducing the endophytic pathogen Sporisorium reiliana
Head smut is a soil-borne systemic maize disease caused by the causal pathogen Sporisorium reiliana. ZmWAK is the gene within the major QTL qHSR1 conferring resistance to head smut disease. ZmWAK has been transfe...
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Article
Flowers with caffeinated nectar receive more pollination
Floral nectar functions to attract insects, so the inclusion of toxic compounds calls for explanation. Recent work shows that honeybees prefer nectars with low concentrations of caffeine and nicotine, and that...
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Article
Successful Treatment of a Necrotizing Fasciitis Patient Caused by Mucor indicus with Amphotericin B and Skin Grafting
Cutaneous mucormycosis, an uncommon disease caused by Mucorales, predominantly occurs in immunocompromised host. The present case is a primary cutaneous mucormycosis due to Mucor indicus in an immunocompetent ind...
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Article
Iron and zinc binding activity of Escherichia coli topoisomerase I homolog YrdD
YrdD, a homolog of the C-terminal zinc-binding region of Escherichia coli topoisomerase I, is highly conserved among proteobacteria and enterobacteria. However, the function of YrdD remains elusive. Here we repor...
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Article
Competition of zinc ion for the [2Fe–2S] cluster binding site in the diabetes drug target protein mitoNEET
Human mitochondrial protein mitoNEET is a novel target of type II diabetes drug pioglitazone, and contains a redox active [2Fe–2S] cluster that is hosted by a unique ligand arrangement of three cysteine and on...
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Article
Marker-assisted introgression of qHSR1 to improve maize resistance to head smut
Head smut, one of the most devastating diseases in maize, causes severe yield losses worldwide. Resistance to head smut has been proven to be a quantitative inherited trait. In our previous study, a major resi...
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Article
Escherichia coli topoisomerase I is an iron and zinc binding protein
Escherichia coli topoisomerase I (TopA) cleaves and rejoins one strand of double-stranded DNA to relax the negatively supercoiled DNA. Structurally, TopA contains an N-terminal catalytic fragment and a C-terminal...
