14 Result(s)
within
Guanzhi Chen
English
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Article
Open AccessCombined effect of adiposity and elevated inflammation on incident type 2 diabetes: a prospective cohort study
Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris...
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Article
Open AccessTemporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have long been proposed to contribute to CVD. However, the temporal relationship between them...
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Article
Open AccessRelationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we a...
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Article
Open AccessCumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study
The relationship of cumulative remnant-cholesterol (Cum-RC) concentration with the risk of cardiovascular disease (CVD) in patients with hypertension remains unclear.
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Article
Open AccessRelationship between cumulative exposure to triglyceride-glucose index and heart failure: a prospective cohort study
High triglyceride-glucose index (TyG) is a major risk factor for heart failure, but the long-term effect of high TyG index on the risk of develo** heart failure remains unclear. Therefore, we aimed to determ...
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Article
Open AccessTemporal relationship between atherogenic dyslipidemia and inflammation and their joint cumulative effect on type 2 diabetes onset: a longitudinal cohort study
Concurrent atherogenic dyslipidemia and elevated inflammation are commonly observed in overt hyperglycemia and have long been proposed to contribute to diabetogenesis. However, the temporal relationship betwee...
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Article
Open AccessTriglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact ...
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Article
Open AccessRelationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort
A single measurement of the triglyceride-glucose (TyG) index, a simple and reliable surrogate marker of insulin resistance, is associated with ischemic stroke. However, evidence for an effect of a long-term el...
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Article
Comparison of immunological properties of recombinant and natural turbot (Scophthalmus maximus) parvalbumin
Fish parvalbumin is a major allergen known to cause allergy and has been a serious concern of food safety all over the world. Recombinant allergen has been broadly applied in allergy diagnosis and immunotherap...
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Article
Allergenicity determination of Turbot parvalbumin for safety of fish allergy via dendritic cells, RBL‐2H3 cell and mouse model
Fish as an important food source, with the increase of consumption rate, the resulting allergic phenomenon increased year by year. Food allergen in aquatic products was an important allergy-inducing factor, wh...
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Article
Open AccessCorrelation of triglyceride to high-density lipoprotein cholesterol ratio with nonalcoholic fatty liver disease among the non-obese Chinese population with normal blood lipid levels: a retrospective cohort research
Although nonalcoholic fatty liver disease (NAFLD) is commonly seen in metabolic abnormalities patients, NAFLD is also occurred in the non-obese individuals. The ratio of triglyceride to high-density lipoprotei...
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Article
Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice
Atopic dermatitis (AD) is a common chronic inflammatory skin disease characterized with high heterogeneity. Recent studies have suggested that it is driven by both terminal keratinocyte differentiation defects...
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Article
Comparative study on the allergenicity of different Litopenaeus vannamei extract solutions
Allergen extracts are widely used for allergy diagnosis and treatment. The application of shrimp extract is hampered due to the low protein concentration and the inconsistent allergenicity. Extracting solution...
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Article
Open AccessPsychological characteristics in high-risk MSM in China
Men who have sex with men (MSM) have become a high-risk group of HIV infection in China. To date, little is known regarding the behavioral, social and psychological characteristics in Chinese MSM, which makes ...
