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Article
Open AccessCombined effect of adiposity and elevated inflammation on incident type 2 diabetes: a prospective cohort study
Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris...
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Article
Open AccessTemporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have long been proposed to contribute to CVD. However, the temporal relationship between them...
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Article
Open AccessRelationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we a...
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Article
Open AccessCumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study
The relationship of cumulative remnant-cholesterol (Cum-RC) concentration with the risk of cardiovascular disease (CVD) in patients with hypertension remains unclear.
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Article
Open AccessRelationship between cumulative exposure to triglyceride-glucose index and heart failure: a prospective cohort study
High triglyceride-glucose index (TyG) is a major risk factor for heart failure, but the long-term effect of high TyG index on the risk of develo** heart failure remains unclear. Therefore, we aimed to determ...
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Article
Open AccessTriglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact ...
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Article
Open AccessRelationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort
A single measurement of the triglyceride-glucose (TyG) index, a simple and reliable surrogate marker of insulin resistance, is associated with ischemic stroke. However, evidence for an effect of a long-term el...