![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
4,585 Result(s)
-
Article
Open AccessPDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system
Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy...
-
Article
Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
-
Article
Open AccessA comparative study of shockwave intravascular lithotripsy and conventional percutaneous coronary intervention in the treatment of severe coronary artery calcification lesions
The purpose of this study was to evaluate the effectiveness of intravascular lithotripsy (IVL) in the treatment of severe coronary artery calcification (CAC) lesions.
-
Article
Surface diffraction beamline at the SSRF
BL02U2 of the Shanghai Synchrotron Radiation Facility is a surface diffraction beamline with a photon flux of 5.5 × 1012 photons/s at 10 keV and a beam size of 160 µm × 80 µm at the sample site. It is dedicated t...
-
Article
3D printed kenics static micromixer
Kenics static mixer (KSM), which comprises helical blades twisted 180° in left and right-hand directions alternatively and connected 90° to each other, has been widely used in macroscale because of its excelle...
-
Article
Phylogenomics, divergence times and notes of orders in Basidiomycota
Basidiomycota is one of the major phyla in the fungal tree of life. The outline of Basidiomycota provides essential taxonomic information for researchers and workers in mycology. In this study, we present a ti...
-
Article
Enhancing coercivity and thermal stability of (Nd,Y)–Fe–B sintered magnets through lamellar structure design
The incorporation of the high-abundance rare-earth element Y in (Nd,Y)–Fe–B sintered magnets offers an opportunity to reduce the cost of permanent magnetic materials, while promoting the balanced usage of rare...
-
Article
Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
-
Article
Deciphering the complex behavior of piezoelectric neuron systems through bifurcation analysis with the time-domain minimum residual method
In this study, a bifurcation analysis of the piezoelectric neuron system (PNS) is conducted utilizing the time-domain minimum residual method (TMRM). From a biophysical standpoint, integrating piezoelectric de...
-
Article
Open AccessWeChat usage and preservation of cognitive functions in middle-aged and older Chinese adults: indications from a nationally representative survey, 2018–2020
To investigate the associations between the most popular social media platform WeChat usage and cognitive performance among the middle-aged and older Chinese population using data from a nationally representat...
-
Article
Open AccessGestational valproic acid exposure enhances facial stimulation-evoked cerebellar mossy fiber-granule cell transmission via GluN2A subunit-containing NMDA receptor in offspring mice
Valproic acid (VPA) is one of the most effective antiepileptic drugs, and exposing animals to VPA during gestation has been used as a model for autism spectrum disorder (ASD). Numerous studies have shown that ...
-
Article
Open AccessGlobal incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035
To study the historical global incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035.
-
Article
B vitamins and bone health: a meta-analysis with trial sequential analysis of randomized controlled trials
Our study showed that B vitamins did not have significant effect on fracture incidence, bone mineral density, and bone turnover markers. However, the research data of B vitamins on bone mineral density and bon...
-
Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
-
Article
Open AccessLarge-Kernel Attention for 3D Medical Image Segmentation
Automated segmentation of multiple organs and tumors from 3D medical images such as magnetic resonance imaging (MRI) and computed tomography (CT) scans using deep learning methods can aid in diagnosing and tre...
-
Article
Open AccessTargeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury
Reperfusion therapy is critical for saving heart muscle after myocardial infarction, but the process of restoring blood flow can itself exacerbate injury to the myocardium. This phenomenon is known as myocardi...
-
Article
Support Vector Machine-Based Tagged Neutron Method for Explosives Detection
Tagged neutron detection system combined with support vector machine (SVM) is proposed for the detection of explosives hidden inside walls. The detection system was based on an ING-27 neutron generator as neut...
-
Article
A New Process of Chlorine Deep Removal in Zinc Sulfate by Highly Active Copper from Copper Slag
Chloride concentration is one of the important factors that seriously affect the electrolysis of zinc sulfate. The copper slag used in the copper slag dechlorination method has low activity due to long-term st...
-
Article
Improving the Visible Light Absorption and Photocatalytic Degradation Activity of TiO2 Particles Towards MB by Organic Sensitizer Decoration
Due to the advantages of non-toxicity, high chemical stability, high activity and low cost, TiO2 is deemed as ideal material for photocatalytic degradation. However, due to its relatively high band-gap energy, an...
-
Article
Optimization of evaluation method for low nitrogen tolerance in soybean germplasm seedlings
Nitrogen is a critical macro-nutrient for growth and development of soybeans (Glycine max L.). Improving nitrogen use efficiency and develo** low nitrogen tolerance varieties are important approaches to mitigat...