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    Chapter

    Human Genetics of Ebstein Anomaly

    Ebstein anomaly (EA) is a rare, congenital cardiac defect of the tricuspid valve with a birth prevalence between 0.5 and 1 in 20,000 [1]. It is characterized by displacement of the tricuspid valve toward the a...

    Farbod Sedaghat-Hamedani in Congenital Heart Diseases: The Broken Heart (2024)

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    Chapter

    Molecular Pathways and Animal Models of Ebstein’s Anomaly

    Ebstein’s anomaly is a congenital malformation of the tricuspid valve characterized by abnormal attachment of the valve leaflets, resulting in varying degrees of valve dysfunction. The anatomic hallmarks of th...

    Bjarke Jensen, Gregor U. Andelfinger in Congenital Heart Diseases: The Broken Heart (2024)

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    Open Access

    eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity

    The roles of nitric oxide (NO) and endothelial NO synthase (eNOS) in the regulation of angiogenesis are well documented. However, the involvement of eNOS in the sprouting of endothelial tip-cells at the vascul...

    Tracy L. Smith, Malika Oubaha, Gael Cagnone in Cellular and Molecular Life Sciences (2021)