3 Result(s)

Article

OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation

In bacterial and sterile inflammation of the liver, hepatocyte apoptosis is, in contrast to necroptosis, a common feature. The molecular mechanisms preventing hepatocyte necroptosis and the potential consequen...

Josephin Koschel, Gopala Nishanth, Sissy Just, Kunjan Harit… in Cell Death & Differentiation (2021)

Article

Correction: OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation

Josephin Koschel, Gopala Nishanth, Sissy Just, Kunjan Harit… in Cell Death & Differentiation (2022)

Article

The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2

The cytokine tumor necrosis factor (TNF) critically regulates the intertwined cell death and pro-inflammatory signaling pathways of dendritic cells (DCs) via ubiquitin modification of central effector molecules, ...

Kunjan Harit, Rituparna Bhattacharjee, Kai Matuschewski… in Cell Death & Disease (2023)