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  1. Article

    Open Access

    Challenges for vaccination in the elderly

    The increased susceptibility of the elderly to infection presents a major challenge to public health services. An aging immune system is well documented as the cause of increased infection rates in elderly peo...

    Richard Aspinall, Giuseppe Del Giudice, Rita B Effros in Immunity & Ageing (2007)

  2. Article

    Open Access

    The how’s and what’s of vaccine reactogenicity

    Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...

    Caroline Hervé, Béatrice Laupèze, Giuseppe Del Giudice in npj Vaccines (2019)

  3. Article

    Open Access

    Pharmacy-based interventions to increase vaccine uptake: report of a multidisciplinary stakeholders meeting

    Despite the existence of efficacious vaccines, the burden of vaccine-preventable diseases remains high and the potential health benefits of paediatric, adolescent and adult vaccination are not being achieved d...

    Fiona Ecarnot, Gaetano Crepaldi, Philippe Juvin, John Grabenstein in BMC Public Health (2019)

  4. Article

    Open Access

    Vaccination as a preventative measure contributing to immune fitness

    The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...

    Béatrice Laupèze, Giuseppe Del Giudice, Mark T. Doherty in npj Vaccines (2021)

  5. Article

    Open Access

    Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children

    The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...

    Dmitri Kazmin, Elizabeth A. Clutterbuck, Giorgio Napolitani in npj Vaccines (2023)