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  1. Article

    Open Access

    Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children

    The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...

    Dmitri Kazmin, Elizabeth A. Clutterbuck, Giorgio Napolitani in npj Vaccines (2023)

  2. Article

    Open Access

    Vaccination as a preventative measure contributing to immune fitness

    The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...

    Béatrice Laupèze, Giuseppe Del Giudice, Mark T. Doherty in npj Vaccines (2021)

  3. Article

    Open Access

    The how’s and what’s of vaccine reactogenicity

    Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...

    Caroline Hervé, Béatrice Laupèze, Giuseppe Del Giudice in npj Vaccines (2019)

  4. No Access

    Chapter

    Administration of Vaccines: Current Process, New Technologies and Adjuvants

    Vaccine formulations and administration have travelled a long path since the first vaccines were developed. Progress in pharmaceutical science has taught us a lot about tailoring vaccine formulations and route...

    Giuseppe Del Giudice, Alberta Di Pasquale in Adult Vaccinations (2019)

  5. No Access

    Article

    Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain

    Antibodies elicited by vaccination with influenza vaccine produced in eggs bind more strongly to the egg-adapted vaccine strain than to wild-type circulating strains.

    Donald D Raymond, Shaun M Stewart, Jiwon Lee, Jack Ferdman, Goran Bajic in Nature Medicine (2016)

  6. No Access

    Chapter

    Inactivated and Adjuvanted Influenza Vaccines

    Inactivated influenza vaccines are produced every year to fight against the seasonal epidemics of influenza. Despite the nonoptimal coverage, even in subjects at risk like the elderly, pregnant women, etc., th...

    Giuseppe Del Giudice, Rino Rappuoli in Influenza Pathogenesis and Control - Volume II (2015)