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Article
Open AccessMemory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children
The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...
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Article
Open AccessVaccination as a preventative measure contributing to immune fitness
The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...
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Article
Open AccessThe how’s and what’s of vaccine reactogenicity
Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...
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Administration of Vaccines: Current Process, New Technologies and Adjuvants
Vaccine formulations and administration have travelled a long path since the first vaccines were developed. Progress in pharmaceutical science has taught us a lot about tailoring vaccine formulations and route...
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Article
Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain
Antibodies elicited by vaccination with influenza vaccine produced in eggs bind more strongly to the egg-adapted vaccine strain than to wild-type circulating strains.
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Chapter
Inactivated and Adjuvanted Influenza Vaccines
Inactivated influenza vaccines are produced every year to fight against the seasonal epidemics of influenza. Despite the nonoptimal coverage, even in subjects at risk like the elderly, pregnant women, etc., th...