6 Result(s)
within
Giuseppe Del Giudice
Biomedicine
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Article
Reduced antibody response to the repetitive sequence of the Plasmodium falciparum circumsporozoite protein in mice infected with Plasmodium yoelii blood forms
The immunogenicity of the carrier-free synthetic peptide, (NANP)40, from the repetitive region of the Plasmodium falciparum circumsporozoite (CS) protein was investigated in genetically responder mice (C57BL/6, H...
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Article
Open AccessChallenges for vaccination in the elderly
The increased susceptibility of the elderly to infection presents a major challenge to public health services. An aging immune system is well documented as the cause of increased infection rates in elderly peo...
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Article
Open AccessFighting against a protean enemy: immunosenescence, vaccines, and healthy aging
The progressive increase of the aged population worldwide mandates new strategies to ensure sustained health and well-being with age. The development of better and/or new vaccines against pathogens that affect...
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Article
Open AccessThe how’s and what’s of vaccine reactogenicity
Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...
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Article
Open AccessVaccination as a preventative measure contributing to immune fitness
The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...
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Article
Open AccessMemory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children
The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...
