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Article
Reduced antibody response to the repetitive sequence of the Plasmodium falciparum circumsporozoite protein in mice infected with Plasmodium yoelii blood forms
The immunogenicity of the carrier-free synthetic peptide, (NANP)40, from the repetitive region of the Plasmodium falciparum circumsporozoite (CS) protein was investigated in genetically responder mice (C57BL/6, H...
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Book
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Chapter
Introduction
We have been living with influenza as long as history can remember, and we are so used to the fact that this disease is part of life that we usually do not pay much attention to it. Even the science of influen...
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Chapter
Waiting for a pandemic
After a quiet period of nearly 30 years, influenza strains with hemagglutinin types that have not been seen in humans previously started to jump from birds to man, suggesting the risk of a new influenza pandem...
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Book
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Chapter
Learning from the First Pandemic of the Twenty-First Century
The response to the first influenza pandemic of the twenty-first century was facilitated by years of preparation for a possible pandemic caused by the avian influenza H5N1. The threat of an H5N1 pandemic had l...
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Article
Open AccessThe how’s and what’s of vaccine reactogenicity
Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...
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Article
Open AccessVaccination as a preventative measure contributing to immune fitness
The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...
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Article
Open AccessMemory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children
The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...