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  1. Article

    Reduced antibody response to the repetitive sequence of the Plasmodium falciparum circumsporozoite protein in mice infected with Plasmodium yoelii blood forms

    The immunogenicity of the carrier-free synthetic peptide, (NANP)40, from the repetitive region of the Plasmodium falciparum circumsporozoite (CS) protein was investigated in genetically responder mice (C57BL/6, H...

    Didier Grillot, Antonello Pessi, Antonio S. Verdini in Medical Microbiology and Immunology (1990)

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    Book

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    Chapter

    Introduction

    We have been living with influenza as long as history can remember, and we are so used to the fact that this disease is part of life that we usually do not pay much attention to it. Even the science of influen...

    Rino Rappuoli, Giuseppe Del Giudice in Influenza Vaccines for the Future (2008)

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    Chapter

    Waiting for a pandemic

    After a quiet period of nearly 30 years, influenza strains with hemagglutinin types that have not been seen in humans previously started to jump from birds to man, suggesting the risk of a new influenza pandem...

    Rino Rappuoli, Giuseppe Del Giudice in Influenza Vaccines for the Future (2008)

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    Book

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    Chapter

    Learning from the First Pandemic of the Twenty-First Century

    The response to the first influenza pandemic of the twenty-first century was facilitated by years of preparation for a possible pandemic caused by the avian influenza H5N1. The threat of an H5N1 pandemic had l...

    Giuseppe Del Giudice, Rino Rappuoli in Influenza Vaccines for the Future (2011)

  7. Article

    Open Access

    The how’s and what’s of vaccine reactogenicity

    Reactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic...

    Caroline Hervé, Béatrice Laupèze, Giuseppe Del Giudice in npj Vaccines (2019)

  8. Article

    Open Access

    Vaccination as a preventative measure contributing to immune fitness

    The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect consequences may include maintenance of homeostasis through prevention of infection-induced complications; trained...

    Béatrice Laupèze, Giuseppe Del Giudice, Mark T. Doherty in npj Vaccines (2021)

  9. Article

    Open Access

    Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children

    The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization in this special population. In this study, we perf...

    Dmitri Kazmin, Elizabeth A. Clutterbuck, Giorgio Napolitani in npj Vaccines (2023)