![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Fast and sensitive DNA analysis using changes in the FRET signals of molecular beacons in a PDMS microfluidic channel
A new DNA hybridization analytical method using a microfluidic channel and a molecular beacon-based probe (MB-probe) is described. A stem-loop DNA oligonucleotide labeled with two fluorophores at the 5′ and 3′...
-
Article
Gold nanoparticle aggregation-based highly sensitive DNA detection using atomic force microscopy
The potential ability of atomic force microscopy (AFM) as a quantitative bioanalysis tool is demonstrated by using gold nanoparticles as a size enhancer in a DNA hybridization reaction. Two sets of probe DNA w...
-
Article
Development of a photodiode array biochip using a bipolar semiconductor and its application to detection of human papilloma virus
We describe a DNA microarray system using a bipolar integrated circuit photodiode array (PDA) chip as a new platform for DNA analysis. The PDA chip comprises an 8 × 6 array of photodiodes each with a diameter ...
-
Article
Mesoporous platinum nanoparticles as a peroxidase mimic for the highly sensitive determination of C-reactive protein
The generation of a mesoporous structure in platinum nanoparticles can effectively enhance physical and chemical properties. In this study, mesoporous platinum nanoparticles (MPNs) were synthesized by a soft t...
-
Article
Determination of lysophosphatidylcholine using peroxidase-mimic PVP/PtRu nanozyme
Lysophosphatidylcholine (LPC) can be used as a biomarker for diseases such as cancer, diabetes, atherosclerosis, and sepsis. In this study, we demonstrated the ability of nanozymes to displace the natural deri...