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Application of Alkaline Sucrose Gradient Centrifugation in the Analysis of DNA Replication After DNA Damage

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    Open Access

    SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase

    The cell cycle-dependent engagement of DNA-end resection at DSBs is regulated by phosphorylation of CTIP by CDKs, the central regulators of cell cycle transitions. Cell cycle transitions are also intimately re...

    Fanghua Li, Emil Mladenov, Sharif Mortoga, George Iliakis in Cell Death & Disease (2020)