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Article

SCF^SKP2 regulates APC/C^CDH1-mediated degradation of CTIP to adjust DNA-end resection in G₂-phase

The cell cycle-dependent engagement of DNA-end resection at DSBs is regulated by phosphorylation of CTIP by CDKs, the central regulators of cell cycle transitions. Cell cycle transitions are also intimately re...

Fanghua Li, Emil Mladenov, Sharif Mortoga, George Iliakis in Cell Death & Disease (2020)