Skip to main content

7 Result(s)

within Gang Dong Remove this filter Life Sciences Remove this filter

and

  1. No Access

    Article

    SREBF2 triggers endoplasmic reticulum stress and Bax dysregulation to promote lipopolysaccharide-induced endothelial cell injury

    An increased lipopolysaccharide (LPS) level in patients with cirrhosis induced the dysregulation of sterol regulatory element–binding transcription factor 2 (SREBF2), which participated in the modulation of tu...

    Gang Dong, **aoquan Huang, Ling Wu, Siyu Jiang, Qintian Tan… in Cell Biology and Toxicology (2022)

  2. No Access

    Article

    MMEJ-KO: a web tool for designing paired CRISPR guide RNAs for microhomology-mediated end joining fragment deletion

    **anrong **e, Weizhi Liu, Gang Dong, Qinlong Zhu… in Science China Life Sciences (2021)

  3. Article

    Open Access

    SPATS2, negatively regulated by miR-145-5p, promotes hepatocellular carcinoma progression through regulating cell cycle

    Spermatogenesis associated serine rich 2 (SPATS2) has been reported to contribute to the tumorigenesis of multiple malignancies. The molecular function of SPATS2 in hepatocellular carcinoma (HCC) is still not ...

    Gang Dong, Shanshan Zhang, Shen Shen, Lulu Sun, Xuemei Wang… in Cell Death & Disease (2020)

    Download PDF (4404 KB) View Article

  4. Article

    Open Access

    DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway

    Hepatoblastoma (HB) is the most common hepatic neoplasm in childhood and the therapeutic outcomes remain undesirable due to its recurrence and metastasis. Increasing evidence shows that dipeptidase 1 (DPEP1) h...

    **chun Cui, **n Liu, Qicai Han, Jianming Zhu, Jianhao Li… in Cell Death & Disease (2019)

    Download PDF (3666 KB) View Article

  5. No Access

    Protocol

    Analysis of Three-Dimensional Structures of Exocyst Components

    The exocyst is an octameric protein complex implicated in tethering secretory vesicles to the plasma membrane during exocytosis. To provide a mechanistic understanding of how it functions, it is of critical im...

    Johannes Lesigang, Gang Dong in Yeast Cytokinesis (2016)

  6. No Access

    Article

    The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif

    The exocyst is a large complex that is required for tethering vesicles at the final stages of the exocytic pathway in all eukaryotes. Here we present the structures of the Exo70p subunit of this complex and of...

    Gang Dong, Alex H Hutagalung, Chunmei Fu… in Nature Structural & Molecular Biology (2005)

  7. No Access

    Article

    Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus

    The three-dimensional structure of rice dwarf virus was determined to 6.8 Å resolution by single particle electron cryomicroscopy. By integrating the structural analysis with bioinformatics, the folds of the p...

    Z. Hong Zhou, Matthew L. Baker, Wen Jiang, Matthew Dougherty… in Nature Structural Biology (2001)