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  1. No Access

    Article

    PKB/Akt promotes DSB repair in cancer cells through upregulating Mre11 expression following ionizing radiation

    An elevated DNA-repair capacity in cancer cells leads to radiation resistance and severely limits the efficacy of radiation therapy. Activation of Akt is tightly associated with resistance to radiotherapy, and...

    R Deng, J Tang, J-G Ma, S-P Chen, L-P **a, W-J Zhou, D-D Li, G-K Feng, Y-X Zeng… in Oncogene (2011)

  2. No Access

    Article

    The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

    The c-Jun NH2-terminal kinase (JNK) pathway represents one subgroup of MAP kinases that are activated primarily by cytokines and exposure to environmental stress. Autophagy is a protein-degradation system char...

    D-D Li, L-L Wang, R Deng, J Tang, Y Shen, J-F Guo, Y Wang, L-P **a, G-K Feng… in Oncogene (2009)

  3. No Access

    Article

    Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells

    J-N Liu, R Deng, J-F Guo, J-M Zhou, G-K Feng, Z-S Huang, L-Q Gu, Y-X Zeng… in Leukemia (2007)

  4. No Access

    Article

    Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis

    It has been shown that acetylcholinesterase (AChE) expression was induced during apoptosis and the anti-sense oligonucleotides and siRNA of AChE may prevent apoptosis in various cell types. However, the mechan...

    R Deng, W Li, Z Guan, J-M Zhou, Y Wang, Y-P Mei, M-T Li, G-K Feng, W Huang… in Oncogene (2006)