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  1. Article

    Open Access

    Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer

    The serine/threonine kinase AKT is generally accepted as a promising anticancer therapeutic target. However, the relief of feedback inhibition and enhancement of other survival pathways often attenuate the ant...

    F Yang, R Deng, X-J Qian, S-H Chang, X-Q Wu, J Qin, G-K Feng… in Cell Death & Disease (2014)

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