6 Result(s)
within
G David Poznik
English
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Article
Open AccessIn-solution Y-chromosome capture-enrichment on ancient DNA libraries
As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach—in-solution capture-enrichment—retrieves sequen...
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Article
Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences
Chris Tyler-Smith, Carlos Bustamante and colleagues report an analysis of 1,244 human Y chromosomes from the 1000 Genomes Project. They find that copy number variants have a higher predicted functional impact ...
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Article
Open AccessThe ancestry and affiliations of Kennewick Man
Kennewick Man, a 8,500-year-old male human skeleton discovered in Washington state, USA, has been the subject of scientific and legal controversy; here a DNA analysis shows that Kennewick Man is closer to mode...
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Article
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
The first individual genome from the Clovis culture is presented; the origins and genetic legacy of the people who made Clovis tools have been under debate, and evidence here suggests that the individual is mo...
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Article
Open AccessPhylogenetic applications of whole Y-chromosome sequences and the Near Eastern origin of Ashkenazi Levites
Previous Y-chromosome studies have demonstrated that Ashkenazi Levites, members of a paternally inherited Jewish priestly caste, display a distinctive founder event within R1a, the most prevalent Y-chromosome ...
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Article
Open AccessAnalysis of TBX1 Variation in Patients with Psychotic and Affective Disorders
A significant portion of patients with 22q11 deletion syndrome (22q11DS) develop psychiatric disorders, including schizophrenia and other psychotic and affective symptoms, and the responsible gene/s are assume...
