2 Result(s)
within
Futang Wan
Science, Humanities and Social Sciences, multidisciplinary
Science, multidisciplinary
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Article
Open AccessStructural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants
EDA is a tumor necrosis factor (TNF) family member, which functions together with its cognate receptor EDAR during ectodermal organ development. Mutations of EDA have long been known to cause X‐linked hypohidroti...
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Article
Open AccessCryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme
Ribonuclease P (RNase P) is an essential ribozyme responsible for tRNA 5′ maturation. Here we report the cryo-EM structures of Methanocaldococcus jannaschii (Mja) RNase P holoenzyme alone and in complex with a tR...
