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    Article

    Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology

    This protocol describes assays for assessing heart rate fluctuations in mice or tissue isolated from mice, including by using in vivo telemetry and in vitro electrophysiology of intact sinoatrial network preparat...

    Stefanie Fenske, Rasmus Pröbstle, Franziska Auer, Sami Hassan in Nature Protocols (2016)

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    Article

    Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

    DNA and histone modifications have notable effects on gene expression1. Being the most prevalent internal modification in mRNA, the N6-methyladenosine (m6A) mRNA modification is as an important post-transcription...

    Huilin Huang, Hengyou Weng, Keren Zhou, Tong Wu, Boxuan Simen Zhao, Mingli Sun in Nature (2019)

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    Open Access

    JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

    Minhui Lin, Karin Nebral, Christoph G. W. Gertzen, Ithamar Ganmore in Leukemia (2019)

  4. Article

    Open Access

    Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

    The prerequisite to prevent childhood B-cell acute lymphoblastic leukemia (B-ALL) is to decipher its etiology. The current model suggests that infection triggers B-ALL development through induction of activati...

    Guillermo Rodríguez-Hernández, Friederike V. Opitz, Pilar Delgado in Nature Communications (2019)

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    Article

    Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

    Recent reports have revealed that oligodendrocyte precursor cells (OPCs) are heterogeneous. It remains unclear whether such heterogeneity reflects different subtypes of cells with distinct functions or instead...

    Roberta Marisca, Tobias Hoche, Eneritz Agirre, Laura Jane Hoodless in Nature Neuroscience (2020)

  6. Article

    Open Access

    Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia

    Julia Hauer, Ute Fischer, Franziska Auer, Arndt Borkhardt in Leukemia (2020)

  7. Article

    Open Access

    Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies

    Claudia Saitta, Stefano Rebellato, Laura Rachele Bettini in Blood Cancer Journal (2022)

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    Article

    Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants

    Adela Escudero, Masatoshi Takagi, Franziska Auer, Ulrike Anne Friedrich in Leukemia (2022)

  9. Article

    Open Access

    The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia

    The presence of supernumerary chromosomes is the only abnormality shared by all patients diagnosed with high-hyperdiploid B cell acute lymphoblastic leukemia (HD-ALL). Despite being the most frequently diagnos...

    Ali Farrokhi, Tanmaya Atre, Jenna Rever, Mario Fidanza, Wendy Duey in Leukemia (2024)