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    Article

    Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

    DNA and histone modifications have notable effects on gene expression1. Being the most prevalent internal modification in mRNA, the N6-methyladenosine (m6A) mRNA modification is as an important post-transcription...

    Huilin Huang, Hengyou Weng, Keren Zhou, Tong Wu, Boxuan Simen Zhao, Mingli Sun in Nature (2019)

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    Open Access

    Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

    The prerequisite to prevent childhood B-cell acute lymphoblastic leukemia (B-ALL) is to decipher its etiology. The current model suggests that infection triggers B-ALL development through induction of activati...

    Guillermo Rodríguez-Hernández, Friederike V. Opitz, Pilar Delgado in Nature Communications (2019)