6 Result(s)

Article

Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease

While the past decade has seen meaningful improvements in clinical outcomes for multiple myeloma patients, a subset of patients does not benefit from current therapeutics for unclear reasons. Many gene express...

Mike J. Mason, Carolina Schinke, Christine L. P. Eng, Fadi Towfic, Fred Gruber… in Leukemia (2020)

Article

Synaptic ribbons foster active zone stability and illumination-dependent active zone enrichment of RIM2 and Cav1.4 in photoreceptor synapses

Rod photoreceptor synapses use large, ribbon-type active zones for continuous synaptic transmission during light and dark. Since ribbons are physically connected to the active zones, we asked whether illuminat...

Ekta Dembla, Mayur Dembla, Stephan Maxeiner, Frank Schmitz in Scientific Reports (2020)

Article

Dynamic assembly of ribbon synapses and circuit maintenance in a vertebrate sensory system

Ribbon synapses transmit information in sensory systems, but their development is not well understood. To test the hypothesis that ribbon assembly stabilizes nascent synapses, we performed simultaneous time-la...

Haruhisa Okawa, Wan-Qing Yu, Ulf Matti, Karin Schwarz… in Nature Communications (2019)

Article

Inter- versus intramodal integration in sensorimotor synchronization: a combined behavioral and magnetoencephalographic study

Although the temporal occurrence of the pacing signal is predictable in sensorimotor synchronization tasks, normal subjects perform on-the-beat-tap** to an isochronous auditory metronome with an anticipatory...

Katharina Müller, Gisa Aschersleben, Frank Schmitz… in Experimental Brain Research (2008)

Article

Erratum to: A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations

Peter Felderbauer, Peter Hoffmann, Henrik Einwächter, Kerem Bulut… in BMC Gastroenterology (2004)

Article

A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations

The role of mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene in chronic pancreatitis is still a matter of debate. Active SPINK1 is thought to antagonize activated trypsin. Cases of SPINK1 mut...

Peter Felderbauer, Peter Hoffmann, Henrik Einwächter, Kerem Bulut… in BMC Gastroenterology (2003)