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  1. No Access

    Article

    Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial

    There is controversy regarding the optimal renal-replacement therapy (RRT) modality for critically ill patients with acute kidney injury (AKI).

    Ron Wald, Stephane Gaudry, Bruno R. da Costa… in Intensive Care Medicine (2023)

  2. Article

    Coronavirus disease 2019

    Yaseen M. Arabi, Janet Diaz, François Lamontagne in Intensive Care Medicine (2023)

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  3. Article

    Automated APACHE II and SOFA score calculation using real-world electronic medical record data in a single center

    The integration of illness severity and organ dysfunction scores into clinical practice, including the APACHE II and SOFA scores, has been challenging due to constraints associated to manual score calculation....

    Alexandre Mutchmore, François Lamontagne… in Journal of Clinical Monitoring and Computi… (2023)

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  4. No Access

    Article

    Vitamin C in sepsis

    Paul J. Young, François Lamontagne, Tomoko Fujii in Intensive Care Medicine (2022)

  5. Article

    Open Access

    The evolution of mean arterial pressure in critically ill patients on vasopressors before and during a trial comparing a specific mean arterial pressure target to usual care

    In randomized clinical controlled trials, the choice of usual care as the comparator may be associated with better clinician uptake of the study protocol and lead to more generalizable results. However, if car...

    Marie-Hélène Masse, Neill K. J. Adhikari, Xavier Théroux… in BMC Anesthesiology (2022)

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  6. Article

    Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis

    Corticosteroids are now recommended for patients with severe COVID-19 including those with COVID-related ARDS. This has generated renewed interest regarding whether corticosteroids should be used in non-COVID ...

    Dipayan Chaudhuri, Kiyoka Sasaki, Aram Karkar, Sameer Sharif… in Intensive Care Medicine (2021)

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  7. Article

    The harm of high-frequency oscillatory ventilation (HFOV) in ARDS is not related to a high baseline risk of acute cor pulmonale or short-term changes in hemodynamics

    Federico Angriman, Bruno L. Ferreyro, Lachlan Donaldson… in Intensive Care Medicine (2020)

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  8. No Access

    Article

    Target blood pressure for septic and vasodilatory shock: what is optimal?

    Junki Ishii, Shinichiro Ohshimo, Nobuaki Shime… in Intensive Care Medicine (2018)

  9. No Access

    Article

    Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock

    Guidelines for shock recommend mean arterial pressure (MAP) targets for vasopressor therapy of at least 65 mmHg and, until recently, suggested that patients with underlying chronic hypertension and atheroscler...

    François Lamontagne, Andrew G. Day, Maureen O. Meade… in Intensive Care Medicine (2018)

  10. No Access

    Article

    Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial

    In shock, hypotension may contribute to inadequate oxygen delivery, organ failure and death. We conducted the Optimal Vasopressor Titration (OVATION) pilot trial to inform the design of a larger trial examinin...

    François Lamontagne, Maureen O. Meade, Paul C. Hébert… in Intensive Care Medicine (2016)