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  1. No Access

    Article

    Toxicarioside N induces apoptosis in human gastric cancer SGC-7901 cell by activating the p38MAPK pathway

    Natural plant compounds with potent proliferation inhibition and apoptosis induction properties have been screened as novel anticancer drugs. Toxicarioside N (Tox N) was isolated from the seeds of the tropical...

    Huan-Ge Zhao, Song-Lin Zhou, Ying-Ying Lin, Hao-Fu Dai… in Archives of Pharmacal Research (2018)

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    Article

    Autophagy plays a protective role against apoptosis induced by toxicarioside N via the Akt/mTOR pathway in human gastric cancer SGC-7901 cells

    Toxicarioside N (Tox N), a natural product extract from Antiaris toxicaria, has been reported to induce apoptosis in human gastric cancer cells. However, the mechanism and actual role of autophagy in Tox N-induce...

    Huan-Ge Zhao, Song-Lin Zhou, Ying-Ying Lin, Hua Wang… in Archives of Pharmacal Research (2018)