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Article
Financial distress and its impact on symptom expression in advanced cancer patients
To assess financial distress (FD) and its impact on symptom expression and other quality of life issues
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Article
Personalized goal for insomnia and clinical response in advanced cancer patients
The aim of this study was to assess the Personalized Insomnia Intensity Goal (PIIG), the achievement of Personalized Goal Response (PGR), and Patient Global Impression (PGI) after a comprehensive symptom manag...
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Article
Open AccessOpioid-induced bowel dysfunction: suggestions from a multidisciplinary expert Board
Constipation, one of the adverse effects of opioid therapy with a major impact on quality of life, is still an unmet need for cancer patients, particularly those with an advanced and progressive disease, and f...
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Article
Prevalence of delirium in advanced cancer patients in home care and hospice and outcomes after 1 week of palliative care
The aim of this study was to assess the prevalence of delirium in advanced cancer patients admitted to different palliative care services in Italy and possible related factors. The secondary outcome was to ass...
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Article
Attitudes of palliative home care physicians towards palliative sedation at home in Italy
Information about the attitudes towards palliative sedation (PS) at home is limited.
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Article
Sleep disturbances in advanced cancer patients admitted to a supportive/palliative care unit
The aim of this study was to assess the prevalence of sleep disturbances and possible correlations with associated factors in a sample of patients admitted to an acute palliative/supportive care unit.
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Article
The use of low doses of a sublingual fentanyl formulation for breakthrough pain in patients receiving low doses of opioids
The aim of this study was to prospectively assess the efficacy and safety of low doses of sublingual fentanyl (SLF) for the treatment of breakthrough pain (BTP) in cancer patients in patients who were receivin...
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Article
Age differences in the last week of life in advanced cancer patients followed at home
A retrospective analysis of a consecutive sample of patients admitted to a home care program was performed. Data were recorded in the last week through a backward analysis from the day before death as follows:...
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Article
Prevalence of oral mucositis, dry mouth, and dysphagia in advanced cancer patients
Oral symptoms can be a sign of an underlying systemic condition and have a significant impact on quality of life, nutrition, and cost of care, while these lesions are often studied in the context of cancer tre...
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Article
Orphan symptoms in advanced cancer patients followed at home
Orphan symptoms are rarely assessed, particularly at home. The aim of this multicenter prospective study was to assess the prevalence of these symptoms and eventual factors possibly associated in advanced canc...
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Article
The use of fentanyl buccal tablets for breakthrough pain by using doses proportional to opioid basal regimen in a home care setting
The dose of rapid onset opioids to be given for breakthrough cancer pain (BTcP) is controversial. Dose proportional to the basal opioid regimen seem to be safe and effective in hospital units. However, data in...
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Article
Can malignant bowel obstruction in advanced cancer patients be treated at home?
Eleven advanced cancer patients affected by malignant bowel obstruction (MBO) were treated at home with a combination of octreotide, metoclopramide, morphine, and dexamethasone. In all patients, we observed a ...
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Article
Efficacy and safety of deep, continuous palliative sedation at home: a retrospective, single-institution study
The goal of this study is to evaluate the feasibility and efficacy of palliative sedation at home (PSH) to approach refractory symptoms in dying cancer patients.
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Article
The palliative prognostic score and survival in patients with advanced solid tumors receiving chemotherapy
To evaluate the accuracy of the Palliative Prognostic Score (PaP score) in selecting metastatic gastrointestinal or nonsmall-cell lung cancer patients candidate to palliative chemotherapy.
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Article
Gabapentin in the treatment of severe sweating experienced by advanced cancer patients
Nine patients with advanced cancer suffering from idiopathic severe sweating were treated with gabapentin (600–1,800 mg/day). All patients responded to the treatment; five patients experienced transient drowsi...
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Article
Assessment and treatment of symptoms among Italian medical oncologists
This work was conducted to evaluate symptoms assessment and use of patient-tailored protocols in clinical practice among Italian medical oncologists.
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Article
The Supportive Care Task Force at the University of L’Aquila: 2-years experience
The Supportive Care Task Force (SCTF) was established within the Medical Oncology Department at the University of L’Aquila in May 2002. The missions of the SCTF were to allow systematic evaluation and treatmen...
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Article
Pain evaluation and management: a survey of Italian radiotherapists
The objective of this study was to assess the knowledge possessed and the attitudes held by Italian radiotherapists regarding evaluation and treatment of pain.
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Article
Pruritus in a patient with advanced cancer successfully treated with continuous infusion of granisetron
We present a case of a patient with advanced cancer affected by severe pruritus not related with cholestasis and/or opioid treatment successfully treated with subcutaneous continuous infusion of granisetron (3...