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Chapter and Conference Paper
Inverse Parametric Sequence Alignment
We consider the inverse parametric sequence alignment problem, where a sequence alignment is given and the task is to determine parameter values such that the given alignment is optimal at that parameter setti...
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Chapter
Dynamic Properties of Cell-Cycle and Life-Cycle Networks in Budding Yeast
Dynamic behaviors of protein-protein and protein-DNA interactions in living cells are investigated using the cell-cycle network and life-cycle network in budding yeast as model systems. Our analysis reveals im...
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Article
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target protein-coding mRNAs at the post-transcriptional level. Our previous studies suggest that mir-21 functions as an oncogene an...
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Article
DeST — An integrated building simulation toolkit Part I: Fundamentals
Many building simulation programs have been developed all over the world since the computer-aided simulation technology was first applied in the 1960s. In early 1980s, Tsinghua University has started to develo...
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Article
Identification and quantification of salinomycin in intoxicated human plasma by liquid chromatography–electrospray tandem mass spectrometry
Salinomycin is a polyether ionophore antibiotic that is widely used in poultry and livestock. Exposure of humans to salinomycin via inhalation or ingestion can cause severe toxicity. The aim of the present wor...
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Article
Open AccessRapid detection of porcine circovirus type 2 using a TaqMan-based real-time PCR
Porcine circovirus type 2 (PCV2) and the associated disease postweaning multisystemic wasting syndrome (PMWS) have caused heavy losses in global agriculture in recent decades. Rapid detection of PCV2 is very i...
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Article
Open AccessWhole-cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for rapid identification of bacteria cultured in liquid media
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used for many years to rapidly identify whole bacteria. However, no consistent methodology exists for the ra...
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Chapter and Conference Paper
Toxicity of Cu, Pb, and Zn on Seed Germination and Young Seedlings of Wheat (Triticum aestivum L.)
Seeds and young seedlings of wheat (Triticum aestivum L.) under exposure to Copper (Cu), lead (Pb) and Zinc (Zn) were studied by employing a hydroponic experiment. Addition of Cu or Pb or Zn to the ...
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Article
Open AccessSpecific, simple and rapid detection of porcine circovirus type 2 using the loop-mediated isothermal amplification method
Porcine circovirus type 2 (PCV2) is the causative agent of postweaning multisystemic wasting syndrome (PMWS), and porcine dermatitis and nephropathy syndrome (PDNS). It has caused heavy losses in global agricu...
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Article
Open AccessIntegrating multiple types of data to predict novel cell cycle-related genes
Cellular functions depend on genetic, physical and other types of interactions. As such, derived interaction networks can be utilized to discover novel genes involved in specific biological processes. Epistati...
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Chapter and Conference Paper
Study on Measurement of Class Coupling in Object-Oriented Software
Class coupling is dependency degree among classes, objects or components in object-oriented systems. It is important characteristic of software quality. This paper analyzes the well-known class coupling measur...
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Article
Open AccessMetabonomic analysis of liver tissue from BALB/c mice with d-galactosamine/lipopolysaccharide-induced acute hepatic failure
Compared with biofluids, target tissues and organs more directly reflect the pathophysiological state of a disease process. In this study, a D-galactosamine (GalN) / lipopolysaccharide (LPS)-induced mouse mode...
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Article
Polyvinyl alcohol fibers with functional phosphonic acid group: synthesis and adsorption of uranyl (VI) ions in aqueous solutions
PVA functionalized with vinylphosphonic acid was prepared as a new adsorbent for uranyl (VI) adsorption from aqueous solutions. The vinylphosphonic acid was cografted onto PVA fibers by preirradiation grafting...
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Article
Adsorption behavior of uranium on polyvinyl alcohol-g-amidoxime: Physicochemical properties, kinetic and thermodynamic aspects
Amidoxime-based adsorbents are widely studied as the main adsorbent in the recovery of uranium from seawater. However, the adsorption rate and loading capacity of such adsorbents should be further improved due...
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Article
Activating Transcription Factor 4 Modulates BDNF Release from Microglial Cells
Pathogenic pain is a common sign of many diseases. The mechanism is unclear. Activating transcription factor 4 (ATF4) plays a critical role in cell activation. Brain-derived neurotrophic factor (BDNF) is an im...
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Article
Optimization based integrated control of building HVAC system
Improving the control strategy of building HVAC (heating, ventilation, and air-conditioning) systems can lead to significant energy savings while preserving human comfort requirements. This paper focuses on th...
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Chapter and Conference Paper
Secure Mobility Management for MIPv6 with Identity-Based Cryptography
Mobile IPv6 is an improvement of the original IPv6 protocol, and provides mobility support for IPv6 nodes. However, the security of mobility management is one of the most important issues for MIPv6. Traditiona...
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Article
Evaluating Potential Markers of Spoilage Foods Using a Metabolic Profiling Approach
Food spoilage is one of the most common factors of food poisoning. In this research, we characterized the metabolic features of three spoiled foods using a nontargeted metabolic profiling strategy based on two...
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Article
Open AccessA metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice
Exercise can increase peroxisome proliferator-activated receptor-δ (PPARδ) expression in skeletal muscle. PPARδ regulates muscle metabolism and reprograms muscle fibre types to enhance running endurance. This ...
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Article
GC-MS-based plasma metabolomic investigations of morphine dependent rats at different states of euphoria, tolerance and naloxone-precipitated withdrawal
Long-term or excessive application of morphine leads to tolerance and addiction, which hindered its conventional applications as a drug. Although tremendous progress has been made on the mechanisms of morphine...
