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Article
Open AccessAnalysis of Distribution and Drug Susceptibility Test Results of Pathogenic Bacteria in Diabetic Foot Ulcers
This study aimed to determine the pathogen distribution and drug susceptibility of diabetic foot wound secretions in a tertiary hospital in a coastal area of southeastern China to guide clinical antibiotic sel...
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Article
Open AccessThe effect of physical therapy and mechanical stimulation on dysfunction of lower extremities after total pelvic exenteration in cervical carcinoma patient with rectovesicovaginal fistula induced by radiotherapy: a case report
Total pelvic exenteration is the ultimate solution for rectovesicovaginal fistula caused by radiation therapy, yet total pelvic exenteration frequently causes intraoperative complications and postoperative com...
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Article
Open AccessSex steroid and cognitive function among community-dwelling older men with or without vascular risk factors: a cross-sectional study
The relationship of testosterone and estradiol concentrations with cognitive function among community-dwelling older men was inconclusive. To examine the association of serum testosterone and estradiol concent...
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Article
Effects of mobile Internet use on loneliness among older adults: Health status as a possible moderator?
Mobile Internet use has profoundly affected people's traditional ways of living in the modern era. The elderly are a particular group of individuals. Although older people are less able to learn to use new thi...
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Article
Open AccessLiver indicators affecting the relationship between BMI and hypertension in type 2 diabetes: a mediation analysis
Body mass index (BMI) is an important risk factor for hypertension in diabetic patients. However, the underlying mechanisms remain poorly understood. Although liver-derived biological intermediates may play ir...
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Article
Open AccessWhat are people’s attitudes toward medical insurance fraud whistleblowers? a study from China
Medical insurance fraud has caused huge losses to countries around the world, and public reporting has become an important means to combat medical insurance fraud. The attitude of medical insurance fraud whist...
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Article
Open AccessWhat influences the public’s willingness to report health insurance fraud in familiar or unfamiliar healthcare settings? a cross-sectional study of the young and middle-aged people in China
Young and middle-aged people are important participants in the fight against health insurance fraud. The study aims to investigate the differences in their willingness to report health insurance fraud and the ...
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Article
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production
Circular RNAs (circRNAs) play an important role in regulating the development of human cancers through diverse biological functions. However, the exact molecular mechanisms underlying the role of circRNAs in p...
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Article
Open AccessHorizontal inequity trends of health care utilization in rural China after the medicine and healthcare system reform: based on longitudinal data from 2010 to 2018
To assess the effectiveness of China's medicine and health care reform in promoting equity in health care utilization among rural residents, it is necessary to analyze temporal trends in equity in health care ...
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Article
Factors influencing public opportunistic behavior in the medical insurance field: an empirical study from Northeast China
The purpose of this study is to investigate the factors influencing the occurrence of medical insurance opportunistic behavior among the public in Northeast China and its importance ranking.
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Article
Clinical study of the value of shear wave elastography in evaluating the degree of liver fibrosis in children
To explore the clinical application of shear wave elastography (SWE) in evaluating the degree of liver fibrosis in children.
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Article
Open AccessValue of abdominal ultrasonography in predicting intestinal resection for premature infants with necrotizing enterocolitis
Abdominal ultrasonography (AUS) has been suggested to be valuable in the early detection of necrotizing enterocolitis (NEC).
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Article
Open AccessThe effect of smartphones on the self-rated health levels of the elderly
Due to the penetration of Internet use and the popularity of “Internet + elderly care” among seniors in recent years, the elderly are gradually integrating into the information society. This study examined the...
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Article
Novel mutations in NLRP5 and PATL2 cause female infertility characterized by primarily oocyte maturation abnormality and consequent early embryonic arrest
This study aims to identify the genetic causes of 12 women with primary infertility characterized by primarily oocyte maturation abnormality and consequent early embryonic arrest.
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Article
Gut microbiome alteration as a diagnostic tool and associated with inflammatory response marker in primary liver cancer
Primary liver cancer has high mortality and morbidity worldwide. However, the characteristic of gut microbiota profile and its correlation with inflammation status in liver cancer patients remains largely unkn...
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Article
Open AccessDiabetes and other vascular risk factors in association with the risk of lower extremity amputation in chronic limb-threatening ischemia: a prospective cohort study
Patients with diabetes are at increased risk of develo** chronic limb-threatening ischemia (CLTI) due to peripheral arterial disease, and this often results in lower extremity amputation (LEA). Little is kno...
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Article
Open AccessIL-7 and CCL19-secreting CAR-T cell therapy for tumors with positive glypican-3 or mesothelin
Although chimeric antigen receptor (CAR)-engineered T cells have shown great success in the treatment of B cell malignancies, this strategy has limited efficacy in patients with solid tumors. In mouse CAR-T ce...
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Article
Novel Mutations in CDC20 Are Associated with Female Infertility Due to Oocyte Maturation Abnormality and Early Embryonic Arrest
The cell division cycle 20 (CDC20) protein is a co-activator of anaphase-promoting complex/cyclosome (APC/C), required for mitotic exit and also meiotic exit, containing seven WD40 repeats in the C-terminus re...
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Article
Open AccessCorneal nerve structure in patients with primary Sjögren’s syndrome in China
The aim of this study was to evaluate the in vivo confocal microscopic morphology of corneal subbasal nerves and its relationship with clinical parameters in patients with primary Sjögren’s syndrome in China.
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Article
Open AccessMetabonomic analysis of liver tissue from BALB/c mice with d-galactosamine/lipopolysaccharide-induced acute hepatic failure
Compared with biofluids, target tissues and organs more directly reflect the pathophysiological state of a disease process. In this study, a D-galactosamine (GalN) / lipopolysaccharide (LPS)-induced mouse mode...