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945 Result(s)
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Article
Correction: Surgical margins and prognosis of borderline and malignant phyllodes tumors
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Article
Open AccessUnraveling the mechanism of assimilatory nitrate reduction and methane oxidation by Methylobacter sp. YHQ through dual N-O isotope analysis and kinetic modeling
Assimilatory nitrate reduction and methane (CH4) oxidation by bacteria play important roles in carbon (C) and nitrogen (N) biogeochemical cycles. Here, an investigation of enzymatic assimilatory nitrate reduction...
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Open AccessCombination therapy of KRAS G12V mRNA vaccine and pembrolizumab: clinical benefit in patients with advanced solid tumors
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Open AccessPNSC928, a plant-derived compound, specifically disrupts CtBP2-p300 interaction and reduces inflammation in mice with acute respiratory distress syndrome
Prior research has highlighted the involvement of a transcriptional complex comprising C-terminal binding protein 2 (CtBP2), histone acetyltransferase p300, and nuclear factor kappa B (NF-κB) in the transactiv...
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Open AccessAURKB/CDC37 complex promotes clear cell renal cell carcinoma progression via phosphorylating MYC and constituting an AURKB/E2F1-positive feedforward loop
As the second most common malignant tumor in the urinary system, renal cell carcinoma (RCC) is imperative to explore its early diagnostic markers and therapeutic targets. Numerous studies have shown that AURKB...
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Open AccessDirect in-situ imaging of electrochemical corrosion of Pd-Pt core-shell electrocatalysts
Corrosion of electrocatalysts during electrochemical operations, such as low potential - high potential cyclic swap**, can cause significant performance degradation. However, the electrochemical corrosion dy...
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Article
Open AccessA self-amplifying loop of TP53INP1 and P53 drives oxidative stress-induced apoptosis of bone marrow mesenchymal stem cells
Bone marrow mesenchymal stem cell (BMSC) transplantation is a promising regenerative therapy; however, the survival rate of BMSCs after transplantation is low. Oxidative stress is one of the main reasons for t...
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Open AccessDoes enrolling in finance-related majors improve financial habits? A case study of China’s college students
There is a growing awareness of the importance of financial management skills. However, few studies have systematically examined this topic in China’s current higher education (HE) system. In this study, we ex...
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Open AccessUpcycling of polyethylene to gasoline through a self-supplied hydrogen strategy in a layered self-pillared zeolite
Conversion of plastic wastes to valuable carbon resources without using noble metal catalysts or external hydrogen remains a challenging task. Here we report a layered self-pillared zeolite that enables the co...
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Article
Open AccessThe relationship between the structural changes in the cervical spinal cord and sensorimotor function of children with thoracolumbar spinal cord injury (TLSCI)
Cross-sectional study.
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Article
Open AccessTherapeutic nanobodies against SARS-CoV-2 and other pathogenic human coronaviruses
Nanobodies, single-domain antibodies derived from variable domain of camelid or shark heavy-chain antibodies, have unique properties with small size, strong binding affinity, easy construction in versatile for...
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Open AccessPD-L1 knockdown suppresses vasculogenic mimicry of non-small cell lung cancer by modulating ZEB1-triggered EMT
PD-L1 overexpression is commonly observed in various malignancies and is strongly correlated with poor prognoses for cancer patients. Moreover, PD-L1 has been shown to play a significant role in promoting angi...
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Open AccessMethodology and real-world applications of dynamic uncertain causality graph for clinical diagnosis with explainability and invariance
AI-aided clinical diagnosis is desired in medical care. Existing deep learning models lack explainability and mainly focus on image analysis. The recently developed Dynamic Uncertain Causality Graph (DUCG) app...
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Open AccessPrimary Ewing’s sarcoma of the uterine cervix: a case report and review of the literature
Ewing’s sarcoma (ES) is an aggressive cancer of bone and soft tissue, most of which tend to occur in the bone. Extraosseous Ewing’s sarcoma (EES) of the cervix is extremely rare.
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Open AccessDeprivation of methionine inhibits osteosarcoma growth and metastasis via C1orf112-mediated regulation of mitochondrial functions
Osteosarcoma is a malignant bone tumor that primarily inflicts the youth. It often metastasizes to the lungs after chemotherapy failure, which eventually shortens patients’ lives. Thus, there is a dire clinica...
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Open AccessAuthor Correction: FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells
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Article
Open AccessA novel model incorporating quantitative contrast-enhanced ultrasound into PI-RADSv2-based nomogram detecting clinically significant prostate cancer
The diagnostic accuracy of clinically significant prostate cancer (csPCa) of Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) is limited by subjectivity in result interpretation and the false p...
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Article
Open AccessA non-invasive method to determine core temperature for cats and dogs using surface temperatures based on machine learning
Rectal temperature (RT) is an important index of core temperature, which has guiding significance for the diagnosis and treatment of pet diseases.
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Open AccessPharmaceutical treatment status of patients with COPD in the community based on medical Internet of Things: a real-world study
This study aimed to investigate the real-world standardisation and adherence of medical treatment regimens in patients with chronic obstructive pulmonary disease (COPD) in the community for making future manag...
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Open AccessCupriavidus B-7 immobilized biochar: an effective solution for Cd accumulation alleviation and growth promotion in pakchoi (Brassica Chinensis L.)
Cd contamination, especially in farmland soil, can pose serious threats to human health as well as ecological security. Stabilization is an important strategy for agricultural soil Cd remediation. In this stud...