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Article
Hypotensive episodes at 24-h ambulatory blood pressure monitoring predict adverse outcomes in Parkinson’s disease
Neurogenic orthostatic hypotension (nOH) is a frequent nonmotor feature of Parkinson’s disease (PD), associated with adverse outcomes. Recently, 24-h ambulatory blood pressure monitoring (ABPM) showed good acc...
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Article
Open AccessBurden of caregiving for cardiovascular dysautonomia in Parkinson’s disease
We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular care to a friend, partne...
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Article
Open AccessDifferential impact of individual autonomic domains on clinical outcomes in Parkinson’s disease
While autonomic failure is a well-known prognostic factor for more aggressive disease progression in Parkinson’s disease (PD), with a three- to sevenfold higher risk of dementia and death within 10 years after...
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Article
Open AccessMachine learning applied to ambulatory blood pressure monitoring: a new tool to diagnose autonomic failure?
Autonomic failure (AF) complicates Parkinson’s disease (PD) in one-third of cases, resulting in complex blood pressure (BP) abnormalities. While autonomic testing represents the diagnostic gold standard for AF...
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Article
Blood pressure circadian rhythm alterations in alpha-synucleinopathies
We sought to analyze the blood pressure (BP) circadian rhythm in Parkinson’s disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF) and to evaluate the effect of vasoactive and dopaminer...
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Article
Cardiovascular autonomic neuropathy and falls in Parkinson disease: a prospective cohort study
Falls represent one of the main complications of Parkinson’s disease (PD), significantly lowering quality of life. Cardiovascular autonomic neuropathy (cAN) is one of the key contributing factors to PD-associa...