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    Article

    Hypotensive episodes at 24-h ambulatory blood pressure monitoring predict adverse outcomes in Parkinson’s disease

    Neurogenic orthostatic hypotension (nOH) is a frequent nonmotor feature of Parkinson’s disease (PD), associated with adverse outcomes. Recently, 24-h ambulatory blood pressure monitoring (ABPM) showed good acc...

    Fabrizio Vallelonga, Matteo Valente, Marta Maria Tangari in Clinical Autonomic Research (2024)

  2. Article

    Open Access

    Burden of caregiving for cardiovascular dysautonomia in Parkinson’s disease

    We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular care to a friend, partne...

    Claudia Ledda, Elisa Montanaro, Gabriele Imbalzano in Clinical Autonomic Research (2022)

  3. Article

    Open Access

    Differential impact of individual autonomic domains on clinical outcomes in Parkinson’s disease

    While autonomic failure is a well-known prognostic factor for more aggressive disease progression in Parkinson’s disease (PD), with a three- to sevenfold higher risk of dementia and death within 10 years after...

    Katherine Longardner, Aristide Merola, Irene Litvan in Journal of Neurology (2022)

  4. Article

    Open Access

    Machine learning applied to ambulatory blood pressure monitoring: a new tool to diagnose autonomic failure?

    Autonomic failure (AF) complicates Parkinson’s disease (PD) in one-third of cases, resulting in complex blood pressure (BP) abnormalities. While autonomic testing represents the diagnostic gold standard for AF...

    Fabrizio Vallelonga, G. Sobrero, A. Merola, M. Valente, M. Giudici in Journal of Neurology (2022)

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    Article

    Blood pressure circadian rhythm alterations in alpha-synucleinopathies

    We sought to analyze the blood pressure (BP) circadian rhythm in Parkinson’s disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF) and to evaluate the effect of vasoactive and dopaminer...

    Fabrizio Vallelonga, Cristina Di Stefano, Aristide Merola in Journal of Neurology (2019)

  6. No Access

    Article

    Cardiovascular autonomic neuropathy and falls in Parkinson disease: a prospective cohort study

    Falls represent one of the main complications of Parkinson’s disease (PD), significantly lowering quality of life. Cardiovascular autonomic neuropathy (cAN) is one of the key contributing factors to PD-associa...

    Alberto Romagnolo, Maurizio Zibetti, Aristide Merola in Journal of Neurology (2019)