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    Article

    Expression array analysis of the hepatocyte growth factor invasive program

    Signaling by human hepatocyte growth factor (hHGF) via its cell surface receptor (MET) drives mitogenesis, motogenesis and morphogenesis in a wide spectrum of target cell types and embryologic, developmental ...

    Fabiola Cecchi, Chih-Jian Lih, Young H. Lee in Clinical & Experimental Metastasis (2015)

  2. Article

    Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH

    Trastuzumab has shown a survival benefit in cases of Her2-positive gastroesophageal cancer (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for tr...

    Daniel V. T. Catenacci, Wei-Li Liao, Lei Zhao, Emma Whitcomb in Gastric Cancer (2016)

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    Article

    Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition

    The role of KRAS, when activated through canonical mutations, has been well established in cancer1. Here we explore a secondary means of KRAS activation in cancer: focal high-level amplification of the KRAS gene ...

    Gabrielle S. Wong, ** Zhou, Jie Bin Liu, Zhong Wu, **nsen Xu in Nature Medicine (2018)

  4. Article

    Author Correction: Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition

    In the Supplementary Information originally published with this article, a lane was missing in the β-actin blot in Supplementary Fig. 2. The lane has been added. The error has been corrected in the Supplementa...

    Gabrielle S. Wong, ** Zhou, Jie Bin Liu, Zhong Wu, **nsen Xu in Nature Medicine (2018)