Skip to main content

2 Result(s)

within Fabio Pessina Remove this filter Life Sciences Remove this filter English Remove this filter

and

  1. No Access

    Article

    Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks

    The DNA damage response (DDR) preserves genomic integrity. Small non-coding RNAs termed DDRNAs are generated at DNA double-strand breaks (DSBs) and are critical for DDR activation. Here we show that active DDR...

    Flavia Michelini, Sethuramasundaram Pitchiaya, Valerio Vitelli… in Nature Cell Biology (2017)

  2. No Access

    Article

    Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors

    Damage-induced long non-coding RNAs (dilncRNA) synthesized at DNA double-strand breaks (DSBs) by RNA polymerase II are necessary for DNA-damage-response (DDR) focus formation. We demonstrate that induction of ...

    Fabio Pessina, Fabio Giavazzi, Yandong Yin, Ubaldo Gioia… in Nature Cell Biology (2019)