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    Article

    TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation

    The biological outcome of TMPRSS2:ERG chromosomal translocations in prostate cancer (PC) remains poorly understood. To address this, we compared the transcriptional effects of TMPRSS2:ERG expression in a transgen...

    Z Mounir, F Lin, V G Lin, J M Korn, Y Yu, R Valdez, O H Aina, G Buchwalter in Oncogene (2015)

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    Article

    Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells

    CD4+ CD25+ regulatory T (Treg) cells engage in the maintenance of immunological self-tolerance and homeostasis by limiting aberrant or excessive inflammation. The transcription factor forkhead box P3 (FOXP3) is c...

    Y Gao, F Lin, J Su, Z Gao, Y Li, J Yang, Z Deng, B Liu, A Tsun, B Li in Genes & Immunity (2012)

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    Article

    Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device

    The magnitude of the immune response to a DNA vaccine depends on three criteria—the optimized vector design, the use of a suitable adjuvant and the successful delivery and subsequent expression of the plasmid ...

    K E Broderick, X Shen, J Soderholm, F Lin, J McCoy, A S Khan, J Yan in Gene Therapy (2011)

  4. Article

    Multiple loci in silico map** in inbred lines

    The in silico map** (ISM) technique and its extension represent major advances for novel gene discovery in germplasm resources of inbred lines. However, the techniques suffer from a relatively high false-positi...

    H-Y Lü, M Li, G-J Li, L-L Yao, F Lin, Y-M Zhang in Heredity (2009)

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    Article

    RAPD analysis of genetic diversity and population genetic structure of Stipa krylovii reshov. in Inner Mongolia steppe

    Random amplified polymorphic DNA (RAPD) analysis was used to characterize the genetic diversity and population genetic structure of Stipa krylovii populations in Inner Mongolia steppe of North China. Thirteen 10-...

    J. L. Wang, N. X. Zhao, Y. B. Gai, F. Lin, A. Z. Ren in Russian Journal of Genetics (2006)

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    Article

    Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt

    Proapoptotic nuclear receptor family member Nur77 translocates from the nucleus to the mitochondria, where it interacts with Bcl-2 to trigger apoptosis. Nur77 translocation is induced by certain apoptotic stim...

    Y-H Han, X Cao, B Lin, F Lin, S K Kolluri, J Stebbins, J C Reed, M I Dawson in Oncogene (2006)

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    Article

    Genetic and physical map** of Pi36(t), a novel rice blast resistance gene located on rice chromosome 8

    Blast resistance in the indica cultivar (cv.) Q61 was inherited as a single dominant gene in two F2 populations, F2-1 and F2-2, derived from crosses between the donor cv. and two susceptible japonica cvs. Aichi A...

    X. Q. Liu, L. Wang, S. Chen, F. Lin, Q. H. Pan in Molecular Genetics and Genomics (2005)

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    Article

    Effects of epidermal growth factor (EGF) and colony-stimulating factor-1 (CSF-1) on expression of c-fos in rat mandibular molars: implications for tooth eruption

    The c-fos gene is expressed in the dental follicle of the first mandibular molar of rats. Molecules that accelerate tooth eruption, epidermal growth factor (EGF) and colony-stimulating factor-1 (CSF-1), enhance t...

    G. E. Wise, L. Zhao, F. Lin in Cell and Tissue Research (1996)

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    Article

    Immunolocalization of interleukin-1α in rat mandibular molars and its enhancement after in vivo injection of epidermal growth factor

    Immunolocalization of interleukin-1α in the first mandibular molars of rats from day 0–12 postnatally showed that the protein was localized in the epithelial stellate reticulum adjacent to the dental follicle....

    G. E. Wise, F. Lin, L. Zhao in Cell and Tissue Research (1995)

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    Article

    Culture and characterization of dental follicle cells from rat molars

    Because the dental follicle is necessary for the eruption of teeth of limited eruption, it was the objective of this study to determine if the cells of the follicle could be cultured in vitro. To achieve this,...

    G. E. Wise, F. Lin, W. Fan in Cell and Tissue Research (1992)