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Article
Open AccessArtesunate induces necrotic cell death in schwannoma cells
Established as a potent anti-malaria medicine, artemisinin-based drugs have been suggested to have anti-tumour activity in some cancers. Although the mechanism is poorly understood, it has been suggested that ...
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Article
Open AccessSurvivin is essential for fertile egg production and female fertility in mice
Survivin is the smallest member of the inhibitor of apoptosis protein (IAP) family and acts as a bifunctional protein involved in mitosis regulation and apoptosis inhibition. To identify the physiological role...
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Article
Quantitative trait loci for non-race-specific, high-temperature adult-plant resistance to stripe rust in wheat cultivar Express
Wheat cultivar Express has durable, high-temperature adult-plant (HTAP) resistance to stripe rust (Puccinia striiformis f. sp. tritici). To elucidate the genetic basis of the resistance, Express was crossed with ...
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Article
Molecular map** of genes for race-specific overall resistance to stripe rust in wheat cultivar Express
‘Express’, a hard red spring wheat cultivar that has been widely grown in the western United States, is used to differentiate races of Puccinia striiformis f. sp. tritici, the causal fungal pathogen of wheat stri...
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Article
Genetics and molecular map** of genes for race-specific all-stage resistance and non-race-specific high-temperature adult-plant resistance to stripe rust in spring wheat cultivar Alpowa
Stripe rust, caused by Puccinia striiformis f. sp. tritici, is one of the most widespread and destructive wheat diseases worldwide. Growing resistant cultivars is the preferred control of the disease. The spring ...
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Article
Map** QTL associated with resistance to Fusarium head blight in the Nanda2419 × Wangshuibai population. II: Type I resistance
Fusarium head blight (FHB) is a serious disease in wheat and barley affecting both yield and quality. To identify genes for resistance to infection, the RIL population derived from ‘Nanda2419’ × ‘Wangshuibai’ ...
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Article
Genetic and physical map** of Pi36(t), a novel rice blast resistance gene located on rice chromosome 8
Blast resistance in the indica cultivar (cv.) Q61 was inherited as a single dominant gene in two F2 populations, F2-1 and F2-2, derived from crosses between the donor cv. and two susceptible japonica cvs. Aichi A...
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Article
Map** QTL associated with resistance to Fusarium head blight in the Nanda2419 × Wangshuibai population. I. Type II resistance
Scab disease caused by Fusarium spp. has been a major concern for both wheat producers and consumers. Deployment of scab-resistant varieties is the major strategy to curb this disease. To identify the scab resist...
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Article
Voltage dependent calcium channels in cerebellar granule cell primary cultures
Voltage activated calcium channels were studied in rat cerebellar granule cells in primary culture. Macroscopic currents, carried by 20 mM Ba2+, were measured in the whole-cell configuration. Slowly inactivating ...
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Article
Competitive blockage of the sodium channel by intracellular magnesium ions in central mammalian neurones
The aim of this study was to determine from macroscopic current analysis how intracellular magnesium ions, Mg i 2+ , int...