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Article
Open AccessComparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort
Gestational diabetes mellitus (GDM) has been associated with adverse health outcomes for mothers and offspring. Prevalence of GDM differs by country/region due to ethnicity, lifestyle and diagnostic criteria. ...
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Article
Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO)
The Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO) is a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood pri...
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Article
Open AccessLongitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema
While there is increasing knowledge about the gut microbiome, the factors influencing and the significance of the gut resistome are still not well understood. Infant gut commensals risk transferring multidrug-...
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Article
Open AccessComparison of microbiota and allergen profile in house dust from homes of allergic and non-allergic subjects- results from the GUSTO study
The prevalence of allergic diseases, such as asthma, allergic rhinitis, eczema and food allergy, has been increasing worldwide, as shown in a large number of studies, including the International Study of Asthm...
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Article
Open AccessEffects of infant weight gain on subsequent allergic outcomes in the first 3 years of life
The association between early weight gain and later allergic outcomes has not been well studied. We examined the relation between weight gain and the subsequent development of allergic outcomes in the first 36...
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Article
Open AccessPredictors of allergen sensitization in Singapore children from birth to 3 years
Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensiti...
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Article
Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Article
Open AccessClinical phenotype and allergen sensitization in the first 2 years as predictors of atopic disorders at age 5 years
From a birth cohort of at-risk Asian infants, we prospectively investigated the role of early onset allergen sensitization and clinical phenotypes as risk factors for atopic disorders at the age of 5 years.
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Article
Open AccessMolecular analysis of infant fecal microbiota in an Asian at-risk cohort–correlates with infant and childhood eczema
Studies have suggested that selective microbial targets prevail in the fecal microbiota of infants with eczema. This study evaluated the composition of fecal microbiota of infants who developed eczema in the f...
