14 Result(s)
within
Eun-Ji Kim
Biotechnology
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Article
Crosslinker-free Bovine Serum Albumin-loaded Chitosan/alginate Nanocomplex for pH-responsive Bursting Release of Oral-administered Protein
The application of protein-based drugs in oral delivery system is limited due to the harsh environment of the gastrointestinal (GI) tract. Herein, a pH-responsive nano-sized complex with chitosan (CH) and algi...
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Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria
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Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria
In the 2016 issue of Biotechnology and Bioprocess Engineering (BBE), an error occurred in the research article: Jun-Ho Kim, Nam-Hong Kim, Eun-Ji Kim, Ji Ho Kim, Min-Young Lee, Yung-Hoon Park, Jung Ro Lee, Seon...
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Enhanced of norfloxacin bioavailability using conjugation of isosorbide via enzymatic catalysis
Norfloxacin is a broad-spectrum synthetic antibacterial agent that has been used to treat complicated urinary tract infections. However, the poor water-solubility of norfloxacin limits its bioavailability. The...
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Algicidal effect of hybrid peptides as potential inhibitors of harmful algal blooms
To biochemically characterize synthetic peptides to control harmful algal blooms (HABs) that cause red tides in marine water ecosystems.
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Antibacterial effects of amino acids-grafted water-soluble chitosan against drug-resistant bacteria
Chitosan is an available natural polysaccharide that is biocompatible, biodegradable, and non-toxic. In this study, to enhance the antibacterial activity of water-soluble chitosan (WSC), amino acids with hydro...
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Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae
Streptomyces venezuelae has an inherent advantage as a heterologous host for polyketide production due to its fast rate of growth that cannot be endowed easily through metabolic engineeri...
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Structural and functional characterization of arabidopsis GSK3-like kinase AtSK12
Plant GSK3-like kinases are key regulators that modulate a broad range of physiological processes such as cell growth, stomatal and flower development, responses for abiotic and biotic stress, and carbohydrate...
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Achievements and impacts of glycosylation reactions involved in natural product biosynthesis in prokaryotes
Bioactive natural products, such as polyketides, flavonoids, glycopeptides, and aminoglycosides, have been used as therapeutic agents. Many of them contain structurally diverse sugar moieties attached to the a...
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Article
Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities
A 14-membered macrolide antibiotic narbomycin produced from Streptomyces venezuelae ATCC 15439 is composed of polyketide macrolactone ring and D-desosamine as a deoxysugar moiety, which acts as an important deter...
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A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253
Rapamycin is a macrocyclic polyketide with immunosuppressive, antifungal, and anticancer activity produced by Streptomyces hygroscopicus ATCC 29253. Rapamycin production by a mutant strain (UV2-2) induced by ultr...
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Rapid Quantification of Lipids in Acremonium chrysogenum Using Oil Red O
A method based on staining condition and volume of culture broth for the rapid estimation of the level of intracellular lipids in Acremonium chrysogenum using Oil red O was developed. Lipids in A. chrysogenum wer...
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Genetic engineering of macrolide biosynthesis: past advances, current state, and future prospects
Polyketides comprise one of the major families of natural products. They are found in a wide variety of bacteria, fungi, and plants and include a large number of medically important compounds. Polyketides are ...
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Heterologous production of epothilones B and D in Streptomyces venezuelae
Epothilones, produced from the myxobacterium Sorangium cellulosum, are potential anticancer agents that stabilize microtubules in a similar manner to paclitaxel. The entire epothilone biosynthetic gene cluster wa...
