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Open AccessSpatial epigenome–transcriptome co-profiling of mammalian tissues
Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular states in the tissue context1–5. However, current methods capture on...
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Open AccessAuthor Correction: RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
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Open AccessRADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
Mammalian genomes encode tens of thousands of noncoding RNAs. Most noncoding transcripts exhibit nuclear localization and several have been shown to play a role in the regulation of gene expression and chromat...
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Article
Open AccessA chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins
Alternative splicing is primarily controlled by the activity of splicing factors and by the elongation of the RNA polymerase II (RNAPII). Recent experiments have suggested a new complex network of splicing reg...
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Article
Databases and resources for human small non-coding RNAs
Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different leve...