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A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development

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  1. Article

    Open Access

    Spatial epigenome–transcriptome co-profiling of mammalian tissues

    Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular states in the tissue context15. However, current methods capture on...

    Di Zhang, Yanxiang Deng, Petra Kukanja, Eneritz Agirre, Marek Bartosovic in Nature (2023)

  2. Article

    Open Access

    Author Correction: RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions

    Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki in Nature Communications (2021)

  3. Article

    Open Access

    RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions

    Mammalian genomes encode tens of thousands of noncoding RNAs. Most noncoding transcripts exhibit nuclear localization and several have been shown to play a role in the regulation of gene expression and chromat...

    Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki in Nature Communications (2020)

  4. Article

    Open Access

    A chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins

    Alternative splicing is primarily controlled by the activity of splicing factors and by the elongation of the RNA polymerase II (RNAPII). Recent experiments have suggested a new complex network of splicing reg...

    Eneritz Agirre, Nicolás Bellora, Mariano Alló, Amadís Pagès, Paola Bertucci in BMC Biology (2015)

  5. Article

    Databases and resources for human small non-coding RNAs

    Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different leve...

    Eneritz Agirre, Eduardo Eyras in Human Genomics (2011)