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Article
Open AccessHow local reference panels improve imputation in French populations
Imputation servers offer the exclusive possibility to harness the largest public reference panels which have been shown to deliver very high precision in the imputation of European genomes. Many studies have n...
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Article
Open AccessAccuracy of heritability estimations in presence of hidden population stratification
The heritability of a trait is the proportion of its variance explained by genetic factors; it has historically been estimated using familial data. However, new methods have appeared for estimating heritabilit...
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Article
Open AccessHigh level of inbreeding in final phase of 1000 Genomes Project
The 1000 Genomes Project provides a unique source of whole genome sequencing data for studies of human population genetics and human diseases. The last release of this project includes more than 2,500 sequence...