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    Article

    A Computational Cardiac Model for the Adaptation to Pulmonary Arterial Hypertension in the Rat

    Pulmonary arterial hypertension (PAH) imposes pressure overload on the right ventricle (RV), leading to RV enlargement via the growth of cardiac myocytes and remodeling of the collagen fiber architecture. The eff...

    Reza Avazmohammadi, Emilio A. Mendiola, João S. Soares… in Annals of Biomedical Engineering (2019)

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    Article

    Contractile Adaptation of the Left Ventricle Post-myocardial Infarction: Predictions by Rodent-Specific Computational Modeling

    Myocardial infarction (MI) results in cardiac myocyte death and the formation of a fibrotic scar in the left ventricular free wall (LVFW). Following an acute MI, LVFW remodeling takes place consisting of sever...

    Emilio A. Mendiola, Sunder Neelakantan, Qian **ang… in Annals of Biomedical Engineering (2023)