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  1. No Access

    Article

    No association of NAFLD-related polymorphisms in PNPLA3 and TM6SF2 with all-cause and cardiovascular mortality in an Austrian population study

    Single-nucleotide-polymorphisms in PNPLA3-rs738409 and the TM6SF2-rs58542926, associated with metabolic-dysfunction-associated fatty liver disease (MAFLD), have been discussed as potentially protective for cardio...

    Georg Semmler, Lorenz Balcar, Sarah Wernly, Leonora Datz in Wiener klinische Wochenschrift (2024)

  2. Article

    Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia

    Luca Valenti, Elena Corradini, Leon A. Adams, Elmar Aigner in Nature Reviews Endocrinology (2024)

  3. Article

    Open Access

    Diverticulosis and cardiometabolic risk factors: a systematic literature review

    There is a hypothesis of an association between diverticulosis and metabolic syndrome (MS) or its components, but data on this topic are inconsistent, and a systematic review has not been performed. We conduct...

    Andreas Völkerer, Sarah Wernly in International Journal of Colorectal Disease (2023)

  4. Article

    Consensus Statement on the definition and classification of metabolic hyperferritinaemia

    Hyperferritinaemia is a common laboratory finding that is often associated with metabolic dysfunction and fatty liver. Metabolic hyperferritinaemia reflects alterations in iron metabolism that facilitate iron ...

    Luca Valenti, Elena Corradini, Leon A. Adams, Elmar Aigner in Nature Reviews Endocrinology (2023)

  5. Article

    Open Access

    The association between educational status and colorectal neoplasia: results from a screening cohort

    Educational status is used as a proxy for socioeconomic status. While lower levels of education are generally associated with poorer health, the data on the relationship between educational status and colorect...

    Sarah Wernly, Georg Semmler in International Journal of Colorectal Disease (2023)

  6. No Access

    Article

    Diagnostik- und Therapieleitfaden 2023 für PBC in Österreich

    Die primär biliäre Cholangitis (PBC) ist eine seltene cholestatische Erkrankung der Leber, die unbehandelt bis zur Leberzirrhose fortschreiten kann. Eine effektive Erstlinientherapie mit Ursodeoxycholsäure (UD...

    in Journal für Gastroenterologische und Hepat… (2023)

  7. Article

    Open Access

    PSD3 downregulation confers protection against fatty liver disease

    Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a missing heritability c...

    Rosellina M. Mancina, Kavitha Sasidharan, Anna Lindblom, Ying Wei in Nature Metabolism (2022)

  8. Article

    Open Access

    A sex-specific propensity-adjusted analysis of colonic adenoma detection rates in a screening cohort

    The prevalence of colorectal adenoma and advanced adenoma (AA) differs between sexes. Also, the optimal age for the first screening colonoscopy is under debate. We, therefore, performed a sex-specific and age-...

    Sarah Wernly, Bernhard Wernly, Georg Semmler, Sebastian Bachmayer in Scientific Reports (2021)

  9. Article

    Open Access

    Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease

    Several single-nucleotide polymorphisms have been identified to be disadvantageous or protective in regard to disease severity in patients with non-alcoholic fatty liver disease (NAFLD). However, it is unclear...

    Rafael Paternostro, Katharina Staufer, Stefan Traussnigg in Hepatology International (2021)

  10. Article

    Open Access

    Hepatosteatosis from Lysosomal Acid Lipase Deficiency

    Stephan Zandanell, Florian Primavesi, Elmar Aigner in Journal of Gastrointestinal Surgery (2019)

  11. No Access

    Article

    Relations of vitamin D status, gender and type 2 diabetes in middle-aged Caucasians:Reply to Dr. Guo

    Wolfgang Patsch, Andreas Stadlmayr, Elmar Aigner, Christian Datz in Acta Diabetologica (2016)

  12. No Access

    Article

    A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

    Felix Stickel and colleagues report the results of a genome-wide association study of alcohol-related cirrhosis. They confirm PNPLA3 as a susceptibility locus and identify new association signals in MBOAT7 and TM...

    Stephan Buch, Felix Stickel, Eric Trépo, Michael Way, Alexander Herrmann in Nature Genetics (2015)

  13. Article

    Parathyroid Hormone is Related to Dysplasia and a Higher Rate of Distal Colorectal Adenoma in Women but Not Men

    Molecular and clinical observations provide evidence for a potential role of parathyroid hormone (PTH) in colorectal cancer development. We therefore aimed to assess the association of PTH with regard to color...

    Elmar Aigner, Andreas Stadlmayr, Ursula Huber-Schönauer in Hormones and Cancer (2015)

  14. No Access

    Article

    Relations of vitamin D status, gender and type 2 diabetes in middle-aged Caucasians

    Vitamin D (Vit D) deficiency may be linked to the development of obesity-associated complications such as insulin resistance and type 2 diabetes. We therefore evaluated the relationship of Vit D serum concentr...

    Andreas Stadlmayr, Elmar Aigner, Ursula Huber-Schönauer in Acta Diabetologica (2015)