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    Article

    Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

    Hair cells of the inner ear are so-called because of the hair-like projections, or stereocilia, that protrude from their apical surface. Sound-induced stereocilial motion is thought to be coupled to mechanoele...

    Piotr Kazmierczak, Hirofumi Sakaguchi, Joshua Tokita, Elizabeth M. Wilson-Kubalek in Nature (2007)

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    A structural change in the kinesin motor protein that drives motility

    Kinesin motors power many motile processes by converting ATP energy into unidirectional motion along microtubules. The force-generating and enzymatic properties of conventional kinesin have been extensively st...

    Sarah Rice, Abel W. Lin, Daniel Safer, Cynthia L. Hart, Nariman Naber in Nature (1999)

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    A 32° tail swing in brush border myosin I on ADP release

    BRUSH border myosin I (BBMI) is a single-headed, unconventional myosin from intestinal microvilli, composed of a heavy chain of relative molecular mass 119,000 (Mr 119K) and three calmodulin light chains1–3. Alth...

    James D. Jontes, Elizabeth M. Wilson-Kubalek, Ronald A. Milligan in Nature (1995)

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    A 35-Å movement of smooth muscle myosin on ADP release

    MYOSIN II crossbridges interact with F-actin producing power-strokes of around 100 Å (refs 1, 2), during which the products of ATP hydrolysis are released3–5. This has been postulated to involve an articulation ...

    Michael Whittaker, Elizabeth M. Wilson-Kubalek, Joseph E. Smith, Lynn Faust in Nature (1995)