Page
%P
![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension
The WNK kinases are a recently discovered family of serine-threonine kinases that have been shown to play an essential role in the regulation of electrolyte homeostasis. Intronic deletions in the WNK1 gene result...
-
Article
The structure of a Michaelis serpin–protease complex
Serine protease inhibitors (serpins) regulate the activities of circulating proteases. Serpins inhibit proteases by acylating the serine hydroxyl at their active sites. Before deacylation and complete proteoly...
-
Article
Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition
Mutational studies of a serine proteinase inhibitor (serpin) reveal determinants of its structural rearrangements.