9 Result(s)
within
Elinor L. Sullivan
English
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Article
Open AccessPrenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques
Prenatal cannabis use is associated with adverse offspring neurodevelopmental outcomes, however the underlying mechanisms are relatively unknown. We sought to determine the impact of chronic delta-9-tetrahydro...
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Article
Open AccessPrenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes
With the growing availability of cannabis and the popularization of additional routes of cannabis use beyond smoking, including edibles, the prevalence of cannabis use in pregnancy is rapidly increasing. Howev...
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Article
Open AccessThe association between food desert severity, socioeconomic status, and metabolic state during pregnancy in a prospective longitudinal cohort
Poor metabolic health during pregnancy is associated with health concerns for pregnant individuals and their offspring. Lower socioeconomic status (SES) is one risk factor for poor metabolic health, and may be...
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Article
Open AccessImpaired placental hemodynamics and function in a non-human primate model of gestational protein restriction
Maternal malnutrition increases fetal and neonatal morbidity, partly by affecting placental function and morphology, but its impact on placental hemodynamics are unknown. Our objective was to define the impact...
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Article
Open AccessChronic prenatal delta-9-tetrahydrocannabinol exposure adversely impacts placental function and development in a rhesus macaque model
Cannabis use in pregnancy is associated with adverse perinatal outcomes, which are likely mediated by the placenta. However, the underlying mechanisms and specific vasoactive effects of cannabis on the placent...
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Open AccessBehavioral co** phenotypes and associated psychosocial outcomes of pregnant and postpartum women during the COVID-19 pandemic
The impact of COVID-19-related stress on perinatal women is of heightened public health concern given the established intergenerational impact of maternal stress-exposure on infants and fetuses. There is urgen...
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Open AccessModulations in the offspring gut microbiome are refractory to postnatal synbiotic supplementation among juvenile primates
We and others have previously shown that alterations in the mammalian gut microbiome are associated with diet, notably early life exposure to a maternal high fat diet (HFD). Here, we aimed to further these stu...
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Article
Open AccessGenomic Variants Associated with Resistance to High Fat Diet Induced Obesity in a Primate Model
Maternal obesity contributes to an increased risk of lifelong morbidity and mortality for both the mother and her offspring. In order to better understand the molecular mechanisms underlying these risks, we pr...
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Article
Relevance of animal models to human eating disorders and obesity
This review addresses the role animal models play in contributing to our knowledge about the eating disorders anorexia nervosa (AN) and bulimia nervosa (BN) and obesity.
