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Article
Renal-limited vasculitis with elevated levels of multiple antibodies
Renal-limited vasculitis (RLV) is a type of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis that presents with crescentic glomerulonephritis with no other organ involvement. Although several ...
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Article
Membranous nephropathy associated with pregnancy: an anti-phospholipase A2 receptor antibody-positive case report
Pregnancy and membranous nephropathy (MN) can occur concurrently with nephrotic syndrome. However, the pathophysiology of MN associated with pregnancy remains unclear, including the involvement of anti-M-type ...
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Article
Open AccessPeritonitis due to Mycobacterium abscessus in peritoneal dialysis patients: case presentation and mini-review
Peritoneal dialysis (PD)-associated peritonitis caused by nontuberculous mycobacteria (NTM), including Mycobacterium abscessus (M. abscessus), is a rare but serious complication that forces PD to be withdrawn. Se...
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Article
Open AccessMGeND: an integrated database for Japanese clinical and genomic information
To promote the implementation of genomic medicine, we developed an integrated database, the Medical Genomics Japan Variant Database (MGeND). In its first release, MGeND provides data regarding genomic variatio...
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Article
Open AccessMetagenomic analysis of bacterial species in tongue microbiome of current and never smokers
Cigarette smoking affects the oral microbiome, which is related to various systemic diseases. While studies that investigated the relationship between smoking and the oral microbiome by 16S rRNA amplicon seque...
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Living Reference Work Entry In depth
Artificial Intelligence in Predicting Kidney Function and Acute Kidney Injury
Acute kidney injury (AKI) is a disease defined as an abrupt decline in kidney function and is a common complication in hospitalized patients with high clinical significance. Recently, a model for predicting th...
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Article
Open AccessAssociation between the size of healthcare facilities and the intensity of hypertension therapy: a cross-sectional comparison of prescription data from insurance claims data
Hypertension is a heterogeneous disease for which role sharing in treatment between specialized facilities and small clinics is needed for efficient healthcare provision. However, the Japanese healthcare syste...
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Article
Open AccessHealth improvement framework for actionable treatment planning using a surrogate Bayesian model
Clinical decision-making regarding treatments based on personal characteristics leads to effective health improvements. Machine learning (ML) has been the primary concern of diagnosis support according to comp...
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Reference Work Entry In depth
Artificial Intelligence in Predicting Kidney Function and Acute Kidney Injury
Acute kidney injury (AKI) is a disease defined as an abrupt decline in kidney function and is a common complication in hospitalized patients with high clinical significance. Recently, a model for predicting th...
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Article
Open AccessUse of proton pump inhibitors and macrolide antibiotics and risk of acute kidney injury: a self-controlled case series study
Proton pump inhibitors (PPIs) are widely used for the treatment of gastrointestinal disorders such as peptic ulcer disease and dyspepsia. However, several studies have suggested that PPI use increases the risk...
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Article
Proteinuria frequency and subsequent renal dysfunction in bevacizumab-treated patients: a single center, retrospective, observational study
Proteinuria is a common adverse event observed during treatment with antivascular endothelial growth factor (VEGF) antibodies. Proteinuria is a risk factor for renal dysfunction and cardiovascular complication...
